MRP5 (ABCC5) (NM_001023587) Human 3' UTR Clone
CAT#: SC213255
3' UTR clone of ATP-binding cassette sub-family C (CFTR/MRP) member 5 (ABCC5) transcript variant 2 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | MRP5 (ABCC5) (NM_001023587) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | ABC33; EST277145; MOAT-C; MOATC; MRP5; pABC11; SMRP |
ACCN | NM_001023587 |
Insert Size | 1211 bp |
Sequence Data |
>SC213255 3’UTR clone of NM_001023587
The sequence shown below is from the reference sequence of NM_001023587. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGATGGCTGTATTCTGCGGTCAGAATGAGAGAGTCAAGCTGGGCAGAATCTCTCGCCAAGAGTTCAG CCTTCCTTTGGAGACTGCTCCATCAGTGCCGAGGTGTGTGGGAACAGGCTTCACTGCACCGCCATCTTA CTGAGTTGCTTCACGTGAGGAAAAGGGGGCTTTGGCCCTGTGACTCAGTTCCACATTTTGGATTGCATA CTGGAAAAGAAGCCAATCTTCTTGCTAGTAAACCAGCAACCCGGCTGTATACAGTGGTGACCCAAGCAA TGGATATAAACCTAAAAATCTGAGGGAGGGGAGAGGTGGAATACAGTAGTTCTTGGAATCTGAAGTCTC CTATTTGATCAGGTTATTTCCTGGGACTTGGCAAAAATCTGATTGGTGGGGATCTCCTAGGACCTAGTG GACATCTGGTATTAATTTAATCTCAGGAAAAACAAGAAATTAACCCAGAGAGAGTCTGGGTTTTGGAAT TCAGCGTAGCTACCTCCAGACCGTGGTGTCTGGCCTCCATTTTTGTCTGTCATTCAGCTCTGACTTACA GCTGCAGTCACCTTTGCTATAAGGCACCTGGGTAGAAGGGTGGATGGGCTTCACATCAATTTTTTTCTT CCTTTAGGGTGGGGGATTGGTTTGGCTTTCTTTTGTTGTGGTTTTTTGTTTTATTTTTGTCAAGATTGA TTTTTAGATGCAAGGACTTGAAAAGACCCAGAAGGATGCCACCAGTTTTTCCTTGAGGCCTAGGATTTT TTATTCTGTCCCGAGCAGAGGTAATTCCTCACAACTTAGTGCACCAGTAGCACCAGCCATTTTGAGCAG AGTACCTCTTTGGGGAGCTTTTCGTTTTGTTTTGTTTTTAATTCTCTTTCCTTAGCAGCAAGGTCTTTT TTCCTAGAGAATCTACTCCGTTGCAGAATCATTGCAACCTCAGGAGCCCTCACTGATTGAGTGCTGTCA GCCTGATATACTACTTTGGACTCTGGAAACAGATATGGGTTCTATTCTCTATTTCTACTGTGTGTCGTT AAACAACCGTCGGAGACCAGATGACCTGTTAGATGGCTAGTCCTGTATAACTCGACTCTGTATGTTTCA ATGTATGTTACTGCAATGCTTCACCTGCTGTACAGTGTTTGTGAGATGCTCTTTGAAGATGGTACTTTT ATATTTTTTCATTTTCAATAAAAGTACATTCCTTCCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001023587.3 |
Synonyms | ABC33; EST277145; MOAT-C; MOATC; MRP5; pABC11; SMRP |
Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
Locus ID | 10057 |
MW | 45.8 |
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