ITM2C (NM_030926) Human 3' UTR Clone

Specifications

Product Data
Product Name	ITM2C (NM_030926) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BRI3; BRICD2C; E25; E25C; ITM3
ACCN	NM_030926
Insert Size	1179 bp
Sequence Data	Insert Sequence (showhide) >SC213118 3’UTR clone of NM_030926 The sequence shown below is from the reference sequence of NM_030926. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTGGAGACGCTCATCTGCGGGGTGGTGTGAGGCCCTCCTCCCCCAGAACCCCCTGCCGTGTTCCTCTTT TCTTCTTTCCGGCTGCTCTCTGGCCCTCCTCCTTCCCCCTGCTTAGCTTGTACTTTGGACGCGTTTCTA TAGAGGTGACATGTCTCTCCATTCCTCTCCAACCCTGCCCACCTCCCTGTACCAGAGCTGTGATCTCTC GGTGGGGGGCCCATCTCTGCTGACCTGGGTGTGGCGGAGGGAGAGGCGATGCTGCAAAGTGTTTTCTGT GTCCCACTGTCTTGAAGCTGGGCCTGCCAAAGCCTGGGCCCACAGCTGCACCGGCAGCCCAAGGGGAAG GACCGGTTGGGGGAGCCGGGCATGTGAGGCCCTGGGCAAGGGGATGGGGCTGTGGGGGCGGGGCGGCAT GGGCTTCAGAAGTATCTGCACAATTAGAAAAGTCCTCAGAAGCTTTTTCTTGGAGGGTACACTTTCTTC ACTGTCCCTATTCCTAGACCTGGGGCTTGAGCTGAGGATGGGACGATGTGCCCAGGGAGGGACCCACCA GAGCACAAGAGAAGGTGGCTACCTGGGGGTGTCCCAGGGACTCTGTCAGTGCCTTCAGCCCACCAGCAG GAGCTTGGAGTTTGGGGAGTGGGGATGAGTCCGTCAAGCACAACTGTTCTCTGAGTGGAACCAAAGAAG CAAGGAGCTAGGACCCCCAGTCCTGCCCCCCAGGAGCACAAGCAGGGTCCCCTCAGTCAAGGCAGTGGG ATGGGCGGCTGAGGAACGGGGCAGGCAAGGTCACTGCTCAGTCACGTCCACGGGGGACGAGCCGTGGGT TCTGCTGAGTAGGTGGAGCTCATTGCTTTCTCCAAGCTTGGAACTGTTTTGAAAGATAACACAGAGGGA AAGGGAGAGCCACCTGGTACTTGTCCACCCTGCCTCCTCTGTTCTGAAATTCCATCCCCCTCAGCTTAG GGGAATGCACCTTTTTCCCTTTCCTTCTCACTTTTGCATGTTTTTACTGATCATTCGATATGCTAACCG TTCTCAGCCCTGAGCCTTGGAGAGGAGGGCTGTAACGCCTTCAGTCAGTCTCTGGGGATGAAACTCTTA AATGCTTTGTATATTTTCTCAATTAGATCTCTTTTCAGAAGTGTCTATAGAACAATAAAAATCTTTTAC TTCTGA AGCGGACCGACTTACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCC CAACCTGCCATCACGAGATTTCGATTCCACCGCCGC
Restriction Sites	SgfI-RsrII
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_030926.6
Synonyms	BRI3; BRICD2C; E25; E25C; ITM3
Summary	Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	81618
MW	41.3

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