CD11b (ITGAM) (NM_001145808) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD11b (ITGAM) (NM_001145808) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6
ACCN	NM_001145808
Insert Size	1200 bp
Sequence Data	Insert Sequence (showhide) >SC213025 3’UTR clone of NM_001145808 The sequence shown below is from the reference sequence of NM_001145808. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGGGGTCCCCCGGGGGCCGAACCCCAGTAGCGGCTCCTTCCCGACAGAGCTGCCTCTCGGTGGCCAGCA GGACTCTGCCCAGACCACACGTAGCCCCCAGGCTGCTGGACACGTCGGACAGCGAAGTATCCCCGACAG GACGGGCTTGGGCTTCCATTTGTGTGTGTGCAAGTGTGTATGTGCGTGTGTGCAAGTGTCTGTGTGCAA GTGTGTGCACATGTGTGCGTGTGCGTGCATGTGCACTTGCACGCCCATGTGTGAGTGTGTGCAAGTATG TGAGTGTGTCCAAGTGTGTGTGCGTGTGTCCATGTGTGTGCAAGTGTGTGCATGTGTGCGAGTGTGTGC ATGTGTGTGCTCAGGGGCGTGTGGCTCACGTGTGTGACTCAGATGTCTCTGGCGTGTGGGTAGGTGACG GCAGCGTAGCCTCTCCGGCAGAAGGGAACTGCCTGGGCTCCCTTGTGCGTGGGTGAAGCCGCTGCTGGG TTTTCCTCCGGGAGAGGGGACGGTCAATCCTGTGGGTGAAGACAGAGGGAAACACAGCAGCTTCTCTCC ACTGAAAGAAGTGGGACTTCCCGTCGCCTGCGAGCCTGCGGCCTGCTGGAGCCTGCGCAGCTTGGATGG AGACTCCATGAGAAGCCGTGGGTGGAACCAGGAACCTCCTCCACACCAGCGCTGATGCCCAATAAAGAT GCCCACTGAGGAATGATGAAGCTTCCTTTCTGGATTCATTTATTATTTCAATGTGACTTTAATTTTTTG GATGGATAAGCTTGTCTATGGTACAAAAATCACAAGGCATTCAAGTGTACAGTGAAAAGTCTCCCTTTC CAGATATTCAAGTCACCTCCTTAAAGGTAGTCAAGATTGTGTTTTGAGGTTTCCTTCAGACAGATTCCA GGCGATGTGCAAGTGTATGCACGTGTGCACACACACCACACATACACACACACAAGCTTTTTTACACAA ATGGTAGCATACTTTATATTGGTCTGTATCTTGCTTTTTTTCACCAATATTTCTCAGACATCGGTTCAT ATTAAGACATAAATTACTTTTTCATTCTTTTATACCGCTGCATAGTATTCCATTGTGTGAGTGTACCAT AATGTATTTAACCAGTCTTCTTTTGATATACTATTTTCATTCTCTTGTTATTGCATCAATGCTGAGTTA ATAAATCAAATATATGTCATTTTTGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001145808.2
Synonyms	CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6
Summary	This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Locus ID	3684
MW	44.5

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