HP1 gamma (CBX3) (NM_016587) Human 3' UTR Clone

Specifications

Product Data
Product Name	HP1 gamma (CBX3) (NM_016587) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HECH; HP1-GAMMA; HP1Hs-gamma
ACCN	NM_016587
Insert Size	1429 bp
Sequence Data	Insert Sequence (showhide) >SC212771 3’UTR clone of NM_016587 The sequence shown below is from the reference sequence of NM_016587. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CATTCTTGTCCAGAAGATGAAGCTCAATAATTGTTCACATTGTTCTTTTATATATATTTATATATATAT ATAAAAATTGGGTCTTAGATTTTGATTTACTAGTGTGACAAAATAACTACATCCTAATGAAAATCAAGT TTGATATGTTTGTTTTGAAAGTAGCGTTGGAAGAGTTGTTGGGGGTTTTTTGCATCCATAGCACTGGTT ACTTTGAACAAATAAATAAAAGCTTTCTGTAGTTGCTTCCTTTATCAGAAAAGAACATTTGATACCATG GTATATCATTTCCTCTTCATTAAAGAACAGCTTTTCTAAATGTTGGGGGAAATGTCCATAGTCATTACT CAGTCAAAACTTGTGTTCTCATGAGCCTAAGGACCATTCTAGATTTATTACGTGTTTTTTGTGTGTGTG TGTGTGTGTGTGTGTGTGTGTATCCATAAAATGCATATGTAAATTTTTTTTTGTTTTTAAGCATTCACC CAAACAAAAAAATCACAGGTAAACCCATGTTTCTGAGATGCCATTATTCCAAGCAAAATAAGAGATAAT CCCTTCAAGTTAAATTGAAAATTTTCCTGAAACCATACATTTCAAGTGAAATAAGTAATTCTAGATAGG ACAATTTAAATTGGATAATTTTAAAGTGTCTATAATTGCAGTGGTTTATTTGCAAAATTCCTAAAAGGA AAAATTTTATCACTGCCATCACAGCAGGTTTCCTCATCCAGATGAGGAAACTAGACAAATGCTAGTGTG TTTTAACTAGCTAAACAAAACTAAGTTAAATGAACATTTAAAAGTTTCCCTAGCGGGCCATTCCTTAGC AAAATGTTGGAATCCCTGTTGCTACATTGACTAAAAGGTCATGATGAATGGAATATGTAAGACTTGGCT CATAGAAACCTAATCAGATGGTTAGAGGTGTTGGCAGTTTAGGACCTGCTGTCATAAATGTGTGAACAA CCTTTTGTAACCTAACCTATTGACCTGCATGTTTTTTCTTTACCCCAATTCATTACATGGAGGCTCAAT CTTGAGTTTGCTTTACTGGTTCAGCAAAAGCCAGGAAGAACAACTTTGTAGTAATCAAAATGTTATCCA ACTGTATATTGTTTACTTTATTGTAAATACTGGTGAACAGTGGTTAATAAATAGTTTTATATTCCTTTA TGCAATTATTAGACTTTTTTCTTTATTTGATATGCCTTTACAGTAGAAATAGAAATGCCCACACTCATT GGATTATCTTTGTTTATAAGTTAGATGATACCAGTAAGGCATTACAGTACATATCCTAGATCTTTTGAG CTTACGAGTTTTAAACTTGAATATGTATTTCCACAGGAATGTTTCCACAGTTGGGAAATAAAAGTTTCA TGTGATGCCTAGGGTCAATTGTCTCATTAAAATGAGGTTTTAAATTCTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_016587.4
Synonyms	HECH; HP1-GAMMA; HP1Hs-gamma
Summary	At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
Locus ID	11335
MW	55.5

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