ROC2 (RNF7) (NM_014245) Human 3' UTR Clone

Specifications

Product Data
Product Name	ROC2 (RNF7) (NM_014245) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CKBBP1; rbx2; ROC2; SAG
ACCN	NM_014245
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC212600 3’UTR clone of NM_014245 The sequence shown below is from the reference sequence of NM_014245. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACTGGGTGGTCCAAAGAATCGGCAAATGAGAGTGGTTAGAAGGCTTCTTAGCGCAGTTGTTCAGAGCC CTGGTGGATCTTGTAATCCAGTGCCCTACAAAGGCTAGAACACTACAGGGGATGAATTCTTCAAATAGG AGCCGATGGATCTGTGGTCCTTTGGGACTCATCAAAGCCTTGGTTTAGCATTTTGTCAGTTTTATCTTC AGAAATTCTCTGCGATTAAGAAGATAATTTATTAAAGGTGGTCCTTCCTACCTCTGTGGTGTGTGTCGC GCACACAGCTTAGAAGTGCTATAAAAAAGGAAAGAGCTCCAAATTGAATCACCTTTATAATTTACCCAT TTCTATACAACAGGCAGTGGAAGCAGTTTCAGAGAACTTTTTGCATGCTTATGGTTGATCAGTTAAAAA AGAATGTTACAGTAACAAATAAAGTGCAGTTTAAAACCCAACTCTTACTCTTAATTTGTTCCTAATACG TATTTTTGGCAGGGAGAGGGAACGGTCCATGAAATCTTTATGTGATATAAGGATTTTAAGTTTGGGCCA GTGAACAGGGTAAATAAAATTTAACTTTTGAGCATATGGAATTTTGATTGCCTTTAAAGTTACTATTCT GTATCATTGATTCATCAAGAAAACCTAGATCTGCACTCACCTCACTGTTCAATCATTGAGTGGTAAAGG ACAGAAGTATTTTCTAGTTCTGGTCAGATGATATAATTTTTTTTTTTTTTTTTTGTGGGGGTGAAGTCT TGCTCTGCCACCCAGGCTGGAGTGCAGTGGCATGATGTCAACTCACTGCAACCTCCGCCTCCCGGGTTC AAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGTGTGCCACCACACCCGGCTAAT TTTTGTATTTTTAGTAGAGACGGGATTTCCCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGG TGATTCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGGGCCACTGCACCTGGCCCAGATG ATATAATTTAACTGTGTTTTAGGTAACATGTTAATGAGGGAAAATGTTTACCAGTGTAGCATTGGATCA AAAAGTTTATCACACAGTGTTTTAATAAATGGTTTATTCTGCTTACCTTATTTGAATTGTCATTATAAT TTTATATGCAACCTTAATTTGTCAAGTAAATACTTTCATTTAATTTGAAAGAATTCATATTCATTTGCT CTTTCATTTGACAATAATAAAATTTAAGGTTTATTACCTGGAAAGAGTGCAAGAAAATACTAAACAACT TTATCAAACTGATTCACACTGAGGGGAGGTTATTTTGTAACAAATAATGGACCACAAGTTCATTTTGTA TTCTTCTGTAGTAGAGGCTACTGATATGAATTTAAGAAAAAACCTTAGAATCTTAACTTTTCACATCTG CAGATGCAGTGTGCCATTCTGAATTTTTCAATCTAAGGGATGTGGATACATAGAATGTTTAAAAAGATA ACAATTAGAATGAAAAATTAAAATTATGTATGCTTTTATATGGGTTACTTTTTATTGATCACATTTCTC TGGAAATTTTTCTTTATATTTTTTCACAGTTGTCTTTCTAGCTACTGAAAAAATTATACAAATATCTTT GGCCATTTAAATGTTTATCATTGTGCAGTGAACTGTTTTAGTAACTTTCTGTTTGACCTTTTTAGAAGG TTGCATCCTTAAAATGTGAACCAGATACATGGCTTTGCATTGAAGAGGAAAGCAGTAGAATGTCAGGTT ACTTTAGGCAGTGTGACAGTATATAAATGAAATGTGGAGGATGGTGGTAACAATTTGATTTTCCACACA GCAAAACCACAGTCCCGCCACCTAACAAAGCCCTGTTTATGCCACACACCAGCATCTGAGGGAAGAGGA GGCACTGTGACAAAGCAGCGCTGATGCTGCTCAGCCTGCGATGATTACAGCTCATCTGCACAGCCATC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014245.5
Synonyms	CKBBP1; rbx2; ROC2; SAG
Summary	The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Locus ID	9616
MW	77

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