TLR5 (NM_003268) Human 3' UTR Clone

Specifications

Product Data
Product Name	TLR5 (NM_003268) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MELIOS; SLE1; SLEB1; TIL3
ACCN	NM_003268
Insert Size	1081 bp
Sequence Data	Insert Sequence (showhide) >SC212140 3’UTR clone of NM_003268 The sequence shown below is from the reference sequence of NM_003268. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCGTTGCAAACTGTAGCAACCATCTCCTAATCAAAGGAGCAATTTCCAACTTATCTCAAGCCACAAATA ACTCTTCACTTTGTATTTGCACCAAGTTATCATTTTGGGGTCCTCTCTGGAGGTTTTTTTTTTCTTTTT GCTACTATGAAAACAACATAAATCTCTCAATTTTCGTATCAACACCATGTTCTGTCTCACTAACCTCCA AATGGAAAATAATAGATCTAGAAAATTGCAACTGCCCTTAGAGGTTTCCAGTCTCCATTGATTTTCTTT CAGATCCAATAATACCGTTCTGTCCTGCTGTGTTGATTATGGAATGTATCCTAATCATGGGAAGGGCAC CTTGGGAGAAGTTGCAGATGGCTGACGTGCTTTCTCTAGCATTCAGCTAAAAAATGGGATGGTCCATGA TTCTGCGTTCTCTGTGTTCTGCAAAACAACATTAAGTAGAAAACAAACAGAAGCAGAGGCACATTTCCT TCTTTTGCCACAGAAACAATGCCACTGTTGAGTGCAAGTCACACTTTGTCTCATAGATAAGAGGTGGCC CCAAAGAAGCTGGGATGAATGAGTCACTACCTGTCTTGTGACTGTACTGCACTTCATGTTCTTACCTTC GGCTTCTCCAGGTCTCGCCCTAGTGAGCCAAGAACTTTCTCTCACATGCTGCCTTTATTTAAGCCTGGC CTTCAAGACCTTCCATGATTTATCACCAACCTACCTTTTCAGCTTTGTTTCCTAGCACACCTCATTGAT CAGCTGCTCAGGCTGTTGCATGAAGAACATGGACTTTGCACACAGATCCTGGGTTGAGTTCTGAGTCAG CTGTGTATTAGCCATGTAACCTTGGCCTTGGTATGCCCTTGCTGGACCTACATTTTCTCACGTAACAGC ATCTATGTCATAGAATTCCTGTGAAAATTAAATTGGCCAAGGATGTCAGGGCTTCTCAGATCTTTTCCT TCGTTGCCCTAATGACCACAAGAGAACACATACACTGAAGGCCTCCTGGGGGGCAGTTGCAATTTCACT GAAGTTGTATTTTTTTATCTTAAATGAAATCTATGTGTATTTTCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003268.6
Synonyms	MELIOS; SLE1; SLEB1; TIL3
Summary	This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
Locus ID	7100
MW	41.1

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