PARN (NM_001134477) Human 3' UTR Clone

Specifications

Product Data
Product Name	PARN (NM_001134477) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DAN; DKCB6; PFBMFT4
ACCN	NM_001134477
Insert Size	1046 bp
Sequence Data	Insert Sequence (showhide) >SC211903 3’UTR clone of NM_001134477 The sequence shown below is from the reference sequence of NM_001134477. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACACTCTTTGAAGTTCCTGACACATGGTAACCAAGACCTGAGGGCAGCAAACCGCTGGTGCTGTCGCTG TGAGCAAGAGCCGGCTGGCACATTTGGAAGCCGCACTGTATTTAACTTAATCAAATGTGGTATGGGAGG GGTTGGAAACCAAGTTGTCTCCTGGGGGGGAGAAAACAGGTTTTATTTTTGTGGCTGTGGTTTTTTCCC CTTTTTAATCTAACTGCCTGTTGACATTGACACTCATCACGGTTGTAGGCTGTCATGAATGTGTACGTG CTTAACCAGTGAATTCCGTGTTGCTCTTGTGAGGCCTTTCCTGTCATGACCCAGTGTGCTTAAGAACCT GCCTGATGGGGAGTGTCGGCTGTGAAATCTGCAAAAAGAGCTGACATTCCAGCTGCTGTGATCATGAAT TTGGGGGTGTACTGTCCTGCCTGTGCATCTTCTCGCACTGAGATTTTGAGGCAGTTGCAGCCCTCGGTT AGTCTCCCAGTGGAAAAATCGGTTGTGCCTCCCTGCTTCCCACCATAGCTGCCTGAAAACATGACGCTC TCAAGCTTGTCCTTCCTTCAGGAAGATGTCCACTCATGCCCACCCATGAGAGGGCTTGCCGTATGCCCT GGCCTTTGGGCATATTTATGTAGAGTTCCTTTCTCCTAAGACGTGAGTTTCTCATGGGGGATGTACGAG TAAAAAGGTTAACTTCTGTTCTTATGCGTGGCGCTGTGTTCACTTTCCAGAGTCTCTGTTCGTTTGTTT GGATGGCGGTCTCGGGGTACGGCAGCGTGTGTGCGTACGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTG TGTGTGTGTGTGTGTGTGTGTGAAATCGTGCAAATCTACAACATGTCCCAGCCCATTCTCCGTTGAAAC AGATCACAGCAACGACAAACGCTCATGGCGCTGCTTTGCTCCACCCGCTTCAGATAGATCATTGTTAGA TATTTCACATTTTTGTATGGTGGAAATAAAAATGAAAAATGTATTTCCAAAAGATGAAAATTAAAAACA TTTTCATAGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001134477.3
Synonyms	DAN; DKCB6; PFBMFT4
Summary	The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Locus ID	5073
MW	39.2

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