MAP3K8 (NM_005204) Human 3' UTR Clone

Specifications

Product Data
Product Name	MAP3K8 (NM_005204) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AURA2; c-COT; COT; EST; ESTF; MEKK8; Tpl-2; TPL2
ACCN	NM_005204
Insert Size	1027 bp
Sequence Data	Insert Sequence (showhide) >SC211672 3’UTR clone of NM_005204 The sequence shown below is from the reference sequence of NM_005204. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGGGGACCACCAACGCTTGAATATGGCTGAAGGATGCCATGTTTGCTCTAAATTAAGACAGCATTGATC TCCTGGAGGCTGGTTCTGCTGCCTCTACACAGGGGCCCTGTACAGTGAATGGTGCCATTTTCGAAGGAG CAGTGTGACCTCCTGTGACCCGTGAATGTGCCTCCAAGCGGCCCTGTGTGTTTGACATGTGAAGCTATT TGATATGCACCAGGTCTCAAGGTTCTCATTTCTCAGGTGACGTGATTCTAAGGCAGGAATTTGAGAGTT CACAGAAGGATCGTGTCTGCTGACTGTTTCATTCACTGTGCACTTTGCTCAAAATTTTAAAAATACCAA TCACAAGGATAATAGAGTAGCCTAAAATTACTATTCTTGGTTCTTATTTAAGTATGGAATATTCATTTT ACTCAGAATAGCTGTTTTGTGTATATTGGTGTATATTATATAACTCTTTGAGCCTTTATTGGTAAATTC TGGTATACATTGAATTCATTATAATTTGGGTGACTAGAACAACTTGAAGATTGTAGCAATAAGCTGGAC TAGTGTCCTAAAAATGGCTAACTGATGAATTAGAAGCCATCTGACAGCAGGCCACTAGTGACAGTTTCT TTTGTGTTCCTATGGAAACATTTTATACTGTACATGCTATGCTGAAGACATTCAAAACGTGATGTTTTG AATGTGGATAAAACTGTGTAAACCACATAATTTTTGTACATCCCAAAGGATGAGAATGTGACCTTTAAG AAAAATGAAAACTTTTGTAAATTATTGATGATTTTGTAATTCTTATGACTAAATTTTCTTTTAAGCATT TGTATATTAAAATAGCATACTGTGTATGTTTTATATCAAATGCCTTCATGAATCTTTCATACATATATA TATTTGTAACATTGTAAAGTATGTGAGTAGTCTTATGTAAAGTATGTTTTTACATTATGCAAATAAAAC CCAATACTTTTGTCCAATGTGGTTGGTCAAATCAACTGAATAAATTCAGTATTTTGCCTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005204.4
Synonyms	AURA2; c-COT; COT; EST; ESTF; MEKK8; Tpl-2; TPL2
Summary	This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
Locus ID	1326
MW	39.5

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