Acetylcholinesterase (ACHE) (NM_015831) Human 3' UTR Clone

Specifications

Product Data
Product Name	Acetylcholinesterase (ACHE) (NM_015831) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ACEE; ARACHE; N-ACHE; YT
ACCN	NM_015831
Insert Size	1015 bp
Sequence Data	Insert Sequence (showhide) >SC211570 3’UTR clone of NM_015831 The sequence shown below is from the reference sequence of NM_015831. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCTTCCTCTCCCACCTCCGGCGGCTGTGAACACGGCCTCTTCCCCTACGGCCACAGGGGCCCCTCCTC TAATGAGTGGTCGGACCGTGGGGAAGGGCCCCACTCAGGGATCTCAGACCTAGTGCTCCCTTCCTCCTC AAACCGAGAGACTCACACTGGACAGGGCAGGAGGAGGGGGCCGTGCCTCCCACCCTTCTCAGGGACCCC CACGCCTTTGTTGTTTGAATGGAAATGGAAAAGCCAGTATTCTTTTATAAAATTATCTTTTGGAACCTG AGCCTGACATTGGGGGGAAGTGGGAGGCCCCGGACGGGGTAGCACCCCCCATTGGGGCTATAACGGTCA ACCATTTCTGTCTCTTCTTTTTCCCCCAACCTCCCCCTCCTGTCCCCTCTGTTCCCGTCTTCCGGTCAT TCTTTTCTCCTCCTCTCTCCTTCCTGCTGTCCTTCTCCGGCCCCGCCTCTGCCCTCATCCTCCCTCTCG TCTTTCGCACATTCTCCTGATCCTCTTGCCACCGTCCCACGTGGTCGCCTGCATTTCTCCGTGCGTCCT CCCTGCACTCATACCCCCCCTTCAACCCGCCCAAATGTCCGATCCCCGACCTTCCTCGTGCCGTCCTCC CCTCCCGCCTCGCTGGGCGCCCTGGCCGCAGACACGCTCGACGAGGCGGAGCGCCAGTGGAAGGCCGAG TTCCACCGCTGGAGCTCCTACATGGTGCACTGGAAGAACCAGTTCGACCACTACAGCAAGCAGGATCGC TGCTCAGACCTGTGACCCCGGCGGGACCCCCATGTCCTCCGCTCCGCCCGGCCCCCTAGCTGTATATAC TATTTATTTCAGGGCTGGGCTATAACACAGACGAGCCCCAGACTCTGCCCATCCCCACCCCACCCCGAC GTCCCCCGGGGCTCCCGGTCCTCTGCATGTCTCAGGCTGAGCTCCCTCCCCCGCGGTGCCTTCGCCCCT CTGGGCTGCCAATAAACTGTTACAGCCAAAAAAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015831.2
Synonyms	ACEE; ARACHE; N-ACHE; YT
Summary	Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. AChE activity may constitute a sensitive biomarker of RBC ageing in vivo, and thus, may be of aid in understanding the effects of transfusion[provided by RefSeq, Sep 2019]
Locus ID	43
MW	37.5

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