IRE1 (ERN1) (NM_001433) Human 3' UTR Clone

Specifications

Product Data
Product Name	IRE1 (ERN1) (NM_001433) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	hIRE1p; IRE1; IRE1a; IRE1P
ACCN	NM_001433
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC211360 3’UTR clone of NM_001433 The sequence shown below is from the reference sequence of NM_001433. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGCCCCCAGTGACTCCAGACGCCCTCTGAGCGAGGGCGGCCCCTCTGTTCTGGTGGCCCCAGCTGTGA CTGAGGGCCTGGTCACCACAATTAGAGCTTGATGCCTCCCGGCTTTGCAGGGAGACCAGGCTTCCCAAA CCAAGTGCCTTGAGCTGCCTGCTCTGCAGCCCACAGAGGACAGTGCTGACCCCAGGAAGTGGGAGAAGT GGCCCCTCGTGACCTACAGGGAACTGGGAAGATGCTGGCCCCAAAAGCCTTACGGTCATGATGTCTGCA AAGGAGGGCCTCAGAGACAGCGCGAGTAGCACCCCCAGCCATCTACTGGATAAACTTGCTTCAGACTTT TTAAATTCCTGCTTAATGTCAGTCTACAGGCCTTTCAGGAAGGGAGAGGAGGGAATCGTACATTTTGCT TGCGTGCTGGGACAGCTAGGCTGAGATGCACCAAGTACAGCCTTCACTGGAGACCGGAATTGAGAGGTG GGGGATGCTGAGGAGGGGGAGGACGGAGTTCAGAGGGTGTCGTCCTGCAGTGTGAGATTTCTCATTGAT CACAGATGTGCCCAGAGTAGCCCAGGTCACTGTTAACTAGTGTTTCTGCAGAGGCAGCAGGAGCCATGA GCATGAGGTGTGGCATTAGGGACTGGTCAGCTATGCATGCTGGCAGGTGGGGTTGTGTCTGCAGGTCTC AGAAATGAAGAGGCTGCTCTGTTCTGGAGGCAGCCGTGGCCCAGTGCCAGTGGCCAGAACAGTGGCCTT TGGTGGGTGTGTCCCGGGCCATCTCGGGGTGGTGCTCAGGAGCGCCTGGGGCAAGAGGTAAAGAGTTCC CTGGCCTTCAAGGAGAGCAGCGAAGACCCAGACAGGGGCCAGCCTTCAGGACCAGAGGGAGGCCGCCGA ATGGGACCCTCCTGGTCACCAGGAGAAAGCCCTGGGCCAGCGAGTAGGCAGTCAAACTCCTTCGTCCCC AAGGCCGGTGGAACAAGAGGCTCGTGGTGAGTCAGGGCCAGGGTGGGTGGCCAAGGCCAGGGTCACCGT GTGCTTCATGGGCCAGCTTTTTTGTTTTTCTTGGCAAATTTTAATAACTATATTTTGATTATACTGTAG AATGCTATGTCAGCATAAGTAAGCTAAACTTGAAGCTTTCTTGTGAAGAATAAATGCAAGATAGAATAC ATCTTCTATTTTTTGTGGTACCAAAAATCACCATCCCCTCAAGAGTGTTCATGTATAGAACATTCTCTA ATGCTGAAGAGTAAAACATTATAGCAACACTATGTAAATGTATTGAACAGTATCAAAGAAATAGTCTCT AAATTGTTTGTACCATATTTTTTTTTCTAAACTTAACATAATTTTTAGCTTTAGTTTCAGTCAAAACTT TGTCTTTTCTCTCCCGAGAGCCTTAGAGGTTAAAATGCAATCAGCCTACCGTGTAAGGAGATGTTGTCC ATGTACTTTCTCCAGCCAGTTGGGGGATCATTGCAGCTCAGGCCTGGTGAACTCAGAGATTCCATTCAG TATTAAGAATGGGATTGTTGAATTTTACTCACAGAGAAATCACTGTTTCTTCATGTTGTAAGATGTTTT CTGTTTGTGTATTTGTATCATGGTTACTCATCAAAAGCTCTCATTCTGCCTTTGTAGAATTCAGTTCCC TTCCTTTCATCATAGCTAAAGTGACTTTTTTCCCTACTATTAACGTGATCCTACATCCTTAAATCTCAT CGATTACCTCACTTAGGCCTTGGAACCTTGGCCCTTGGTCGGTGTCCTTGGCGTCTTCTAAGCAAGGCT GTGCGTTGTTCAGAAACGTGGCCAGACCGCATTTCCTGCTGCTCCCATGCCGCATGCCAGGTGGCCTGA GACAGAGCTCCCCATACGGCTGCAAGGTGCTTTACCTGTGGGCTTTGGCAGTAACCCAAGAGAGGATCA GAAGGTGGAGAAGGTGCCACGAGTGATTTAACAGGCCTGCCACAGGGAGTGCCCCCAGCCCAGCTCGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001433.5
Synonyms	hIRE1p; IRE1; IRE1a; IRE1P
Summary	This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. [provided by RefSeq, Aug 2017]
Locus ID	2081
MW	73.2

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