CYP1A1 (NM_000499) Human 3' UTR Clone

Specifications

Product Data
Product Name	CYP1A1 (NM_000499) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
ACCN	NM_000499
Insert Size	977 bp
Sequence Data	Insert Sequence (showhide) >SC211305 3’UTR clone of NM_000499 The sequence shown below is from the reference sequence of NM_000499. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGCACTTCCAAATGCAGCTGCGCTCTTAGGTGCTTGAGAGCCCTGAGGCCTAGACTCTGTCTACCTGG TCTGGTTGGGCAGCCAGACCAGCAGGCTGGCCTATGTGGTCTAAGGTTCAGCCTGAAACTCATAGACAC TGATCTGGCTGCAGTTTTGCTATCTGGGCTGTGGGCAAGCCTAAGGGATCCTGCCTGCCCCTACCCTGG ACTTGCCTCTGCACACCCTCCAGAGACAACAGGTAAAACAGGGCCACATAGATGCTGATGGAGCCTTCC CAAGTTGTGCTTGAGCCAGGAGGCCTGCTAGGGTTAGGAGGTCCTTAGGCCTCTGAGAAGCTCTGAAGA ACTCTCTGGAAGCCCCTGGGCCCAGTACCTAGCTGGCTCTGTGAGGGTGCTGACTGGCTTCAGCAAGTT AGAACTAGCCAAACCAGGACCCTGTCCAATCTTTGACAATTGGGAGCTGCCAAGAGTGAAGGGAAGAGA CAGCCCAGGATACTGGCACAGAGGTAGTCTCACTGCTTGAACTAGGCTGAGCAATCTGACCCTATGGGT CTAGGACACAGTTCCTGGGAACATCACATTCCTCTGCCCTTCCTGCAGGCAGGAACAAACAGGGCTGCC TTCTGGCCTTGTAAGACCCTTATTGCTGTCCTGGAGGGGCTGGGGACTTGTGTCTGCGGGGATCAGAGC GCACAGGGAGTGCACATATCCAGGCACCAGGACTAGGGCTGGAGTGAGGGGGGGGTATTTCAATTACCT TCTATTGGTCTCCCTTCTCTACACTCTTGTAATAAAATGTCTATTTTTAATGTTTGTACACAACAATCC TTCTATTCTAGCCTGCATTGAGCTTGCATGCTTGCATAAGAGCTTAAGAACCATTGATTTAATGTAATA GGGAAAATTCTAACCCAGGTATCCAAAAATGTGTAAGAACAACTACCTGAGCTAAATAAAGATATTGTT CAGAAATCCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000499.5
Synonyms	AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
Summary	This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
Locus ID	1543
MW	35.9

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