PCSK7 (NM_004716) Human 3' UTR Clone

Specifications

Product Data
Product Name	PCSK7 (NM_004716) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	LPC; PC7; PC8; SPC7
ACCN	NM_004716
Insert Size	1690 bp
Sequence Data	Insert Sequence (showhide) >SC211246 3’UTR clone of NM_004716 The sequence shown below is from the reference sequence of NM_004716. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCGCACGGGAAGGAGGAGCAGATCTGCTGACCTCAGGGCCTGACAGTGTGGGACAGGCTCTTCTTTCCC AAAATTAGGGAGCTCTTGACAGAAAGCAGTTCTGATGCTTACATCTGGAATCTGAGGCATCCTCTGACT CCACTCAAAGAGGGTGAGGGCCTTCTTAAGATACAAATGGTGGAGGATTGCTGCCAGAGAAGTCTGGTC AGAGCCACAGGGTCTGCCTCCAGCCAAACGGGAGCTTTTGGTGAGAAGGTGTTGGACAGGGGATTGGCG CCCCCCTTTGGTTTGGCCTCCATCCTCATCTCTCTTGGGCCAAGCCAGCTGCCTAGGTCCCCCAAGCAT GGGGGACCCCTTCCCACATATAAGTTGAGAAGGTGCCTGCCATAGCCAGGAGCGCATCTCAATGGAAAC ATCACTGGGGTCACTTGGGAAGAGGACTTCGGGGTAGAGGCTGGGAGGAGCCCCTGGACATGCCTGTCC TGAAAGCGGCTGCCTCCATTATCCATTCCCAAGATGCCTGATCAGAAACCAACCATGAATGAACCCCTG GCTCCTTCACCACCCCCACGATTGGTATGATGCTGCCGGCACAGCTGGGATACACACGGCTCCCCCAGG CCTGAGCTGCTTCACTAGGGAATCCTGCGGCAGGACTGCAGAGCAGATGGCAGATGCACATGTTGGAGG AGAGAGCCTTGGGAGCCACTGCCACTCCAGTCCTGCCACCACCCTGTCTTCCTCTGCAAGTGCTCAGGG AAATGGCCTTCCCGCCGGAGGCCAGCTATCTGCCTGACAGGCTGTGACTCTTCTCTCAACCTTGGCCTT CTCCCCTCTTCTGAGCTAGTTGGTTGAATTTTTTTTAATGCTTAAGATTTGTTTTTCTCTTTTCACAGC AACATTTTCTTGAATTTTTTTCTGCACAGCTTTTCCAAAATAAAAACCTTCCAAACAATTCTGCCACTC GCAATCTCTCCTTTCCTCTGTCTCCCCAAAGCCACTGCATGCTGCTGAGTGGCTCCTTTTTCCCTTCGG TCCCCAAGATTCACTCTCCTGTTCTATGGCCTGTTTCCTCTGAAAGAATCTGACTGTCCTGGAATCTTG GCACATGAAGGGTCCTTCAGAGGACGGCAGCCAGGAACACATACAAGCCCGAGATGCCTGCCTGTCCCC TGCGCAGATCTGAAACCATAACAAAAGTGACCAGGGCAAATCAAACTCTGCCAGCCAGGCCTGAGAAAA GATTGATTTTTTTTTTTTTTTTTTGAGTTCCAACCCCAAAAATATTCCAGGACAAGATAGGGGGCAGGC TGGGCTGGTTCTTCTTCAATGGGCTTTTGCCGCCAAGGAGGACAGTGGACTTGGCCCACATCCAGGCTA CCCCCAGCCCGCTTCTCCCCTGCTTAGCCCAGGGAGGAGACAGTAGAGGTGATGGGGGCAGCCGGGAGG GAGGGGCCAAGGCAGTGATGCTTTCGGGTAAGAAGTTGGGCTGAGGCTGGGGGCACAGGGAGGAGCTGC CCAGGTGCAGTTACCATTGCTCAGTGACAGAGCCTCAAAGCTTGGCCAGGGCTGAAGGTACCACACGGG TGTGGGTGAGGCAGGCTAAGCGGGATGGCTGCAGCCAAGGAGCTGGGGGAGGGCCGGGCTCAGGGCTAG CCCTCTCCGCTCTAACTGATGATCTGCCGAGGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004716.4
Synonyms	LPC; PC7; PC8; SPC7
Summary	This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq, Feb 2014]
Locus ID	9159
MW	62.2

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