DUSP4 (NM_057158) Human 3' UTR Clone

Specifications

Product Data
Product Name	DUSP4 (NM_057158) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HVH2; MKP-2; MKP2; TYP
ACCN	NM_057158
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC211188 3’UTR clone of NM_057158 The sequence shown below is from the reference sequence of NM_057158. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCCCCATCACCACCTCTCCCAGCTGTTAGAGCCGCCCTGGGGGCCCCAGAACCAGAGCTGGCTCCCAG CAAGGGTAGGACGGGCCGCATGCGGGCAGAAAGTTGGGACTGAGCAGCTGGGAGCAGGCGACCGAGCTC CTTCCCCATCATTTCTCCTTGGCCAACGACGAGGCCAGCCAGAATGGCAATAAGGACTCCGAATACATA ATAAAAGCAAACAGAACACTCCAACTTAGAGCAATAACGGCTGCCGCAGCAGCCAGGGAAGACCTTGGT TTGGTTTATGTGTCAGTTTCACTTTTCCGATAGAAATTTCTTACCTCATTTTTTTAAGCAGTAAGGCTT GAAGTGATGAAACCCACAGATCCTAGCAAATGTGCCCAACCAGCTTTACTAAAGGGGGAGGAAGGGAGG GCAAAGGGATGAGAAGACAAGTTTCCCAGAAGTGCCTGGTTCTGTGTACTTGTCCCTTTGTTGTCGTTG TTGTAGTTAAAGGAATTTCATTTTTTAAAAGAAATCTTCGAAGGTGTGGTTTTCATTTCTCAGTCACCA ACAGATGAATAATTATGCTTAATAATAAAGTATTTATTAAGACTTTCTTCAGAGTATGAAAGTACAAAA AGTCTAGTTACAGTGGATTTAGAATATATTTATGTTGATGTCAAACAGCTGAGCACCGTAGCATGCAGA TGTCAAGGCAGTTAGGAAGTAAATGGTGTCTTGTAGATATGTGCAAGGTAGCATGATGAGCAACTTGAG TTTGTTGCCACTGAGAAGCAGGCGGGTTGGGTGGGAGGAGGAAGAAAGGGAAGAATTAGGTTTGAATTG CTTTTTAAAAAAAAAAGAAAAGAAAAAGACAGCATCTCACTATGTTGCCAAGGCTCATCTTGAGAAGCA GGCGGGTTGGGTGGGAGGAGGAAGAAAGGGAAGAATTAGGTTTGAATTGCTTTTTTAAAAAAAAAGAAA AGAAAAAAAAAGACAGCATCTCACTATGTTGCCAAGGCTCATCTCAAGCTCTTGGGCTCAAGAGATCCT CCCACCTCGGCCTCCTGAGTAGCTGGGACTGCAGGTGTGTGTCATCATGACCAATGTGAATTGCTTTTG AAGCTGGTTCATGGGCATGTAGGCCACCGAAGCAATTTTAGACCACAGTAAGTCAAGCTTTTTTCCCTC CGATGATCACTGGGTGGTTGCAGCATTTTTTGCATAAACCTGCCTAAGACTTGTCTATCGTCTGTGATC AATATGCCATATTACACTAAGGTGCTCCTGGAAAATTGGGTGCAGTTCAAATTTTCCTACAGCAAATCA TTTGGCAAGGCCAGCCATTGGGGAAACCAGACAACTAGAGATAACCCTGAAATGAATCCTTTTGTAAAT TGAAGCACCATCTTTTCTTTTTTTGCATAAATTGGAGGTTTTAATTTTAGGGCAGTTACCTGAAGTGAA ATATACCAACAATTTCTTGTGTTCTTTAAATTCCTAGTTAGGTGAATATTTTTGAAGGTCCTCTTTTGA ATAAAGAGGGGAATGGACACCACATTTCAGGTCTTCTCGAAGTGTGGAAGGGCAAGAGAGCATCAGTGA GCTGATGGTGGATTGCTTACATCGGATTCCATTGGTATGAATTTCCCAAACTGGAAATCAAAGCGCCAG GGTGGGGTTGGGGCTGACTGCTGGTGAGGGGGCTGGCCGCTGGCTCCCGTGACGTGCGTCATGGGCACG CAGGCGCCATTTTGAATCTATCGTCGGCACGTGGGTGCCATTTTGAATCCTTAGTTGGGCCTTTCTAAA TGGAGAATGGCTTTGGAGGGAGACACGTTTTCTGTGGGGAGGGTTTGGGGGGGAGGGAGGAGGGAACAA GCTACATGCTATTTTGTTTGTAGTATTGTGGAACAGTCTTGTTATGGAGTGCCAGCTTAGAGGTTGTTG CAAACTTGTCTAGAAGTGAGAGCATGGTTTTTTTTAGCCCTTTGAGAGTCTACATCTAATGAACATTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_057158.4
Synonyms	HVH2; MKP-2; MKP2; TYP
Summary	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq, Jul 2008]
Locus ID	1846
MW	74.4

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