PKA R2 (PRKAR2A) (NM_004157) Human 3' UTR Clone

Specifications

Product Data
Product Name	PKA R2 (PRKAR2A) (NM_004157) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PKR2; PRKAR2
ACCN	NM_004157
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC211140 3’UTR clone of NM_004157 The sequence shown below is from the reference sequence of NM_004157. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCGTGGATCTGGGCAACCTCGGGCAGTAGGTGTGCCACACCCCAGAGCCTTCTTAGTGTGACACCAAA ACCTTCTGGTCAGCCACAGAACACATACAGAAAACAGACATGACAGAACTGTTCCTGCCGTTGCCGCCA CTGCTGCCATTGCTGTGGTTATGGGCATTTAGAAAACTTGAAAGTCAGCACTAAAGGATGGGCAGAGGT TCAACCCACACCTCCACTTTGCTTCTGAAGGCCCATTCATTAGACCACTTGTAAAGATTACTCCAACCC AGTTTTTATATCTTTGGTTCAAAACGGCATGTCTCTCCAACAATTTAAGTGCCTGATACAAAGTCCAAA GTATAAACATGCTCCTTTCCTCTCTTGCTGCTACTCTTGCTTTTGGAAGTTACCACAGGGTCTGCAGAA ACCTGTTGTATAACTGTAGACACTCTCTAATGGTTCTCAAAGGAGGAAATGTAGCCTTCAGTCTCCTCA TTTGTCCTTTGAGGAAGTCCACATTTGTTCACAGTTGCAGCCTTTGGTTTTACAGTGGGAAATGGTGGT GGATGATATGGACATATGTAGCCCAGTGGCATTGTACTTTCTGCTGACAGCTGCACACATTACAGCTGT CTCCAAACCCACAGTGATGCTTAGGGAAAGACCCTGCTCAGGACCCAGCAGGTCAGCACCCCAGAGCAG ACTGATAGGTCCGTGGGACCCATGTTAGAGCAGAAAATTTGGGCTCAGCACATTTTACTGTTAGTAGAG AGCCAGGAAACGTTTTCTGGGTTGGGGATTTTGTGGGATTTTTTAATTTTTTTAGTAGGTTTTGTTTAA CCTCTGTGCAGTTTGTATGAATGAATTGCTATACATTTATAAGGAGCCAGGGTCTGGAGGGTTGCTATC ACTTTGTCCAGCCCAAATACCTTCCTGGGCAACTCCTACCATTTGTTTGCAGTTGCCTCTACTAGCTGA TGGCAGTATGCTGGAAAGAGGTTGTACTATAAAGAGAGTTCTTTCCTTCTACTCCAGAGTTGTTGTGTA GCTTTGCCATTGAACCGATCAATTTTTAAACTCTTTAAAGAAGCAGCAGCTATTTTTTTGAAATTAAAG AAAATTCTCAGGCCAGGCTCAATGGCTCATGCCTATAATTGTAGTGCTTTGGGAGGCTGAGCTGGGAGG ATCGCTTAAGACCAGCCTAGGCAACAGAGTGAGATCCTGTCTCTACAAAAACAAAAATTTTTTTTTTGT TTTCTTTTTGAGACGGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGTGCGGTCTTGGCTCACC GCAACCTCCGCCTCCCAGATTAAAGTGATTCTCCTGCCTCAACCTCCTGAGTAGCTGGGATTACAGGCA TGCGCCACCATGCCGGGCGAATTTTGTATTTTTAATAGAGACAGGGTTTCTCTGTGTTGGTCAGGCTGG TCTCAAACTCCCAACCTCAGGTGATCCGCCCACCTCAGCCTCTCAGAGTGCTGGGATTACAGATGTGAG CCACTGCACCTGGCAAAAAAAAAATTTTTTTTTAATTTGTCAGGTGTGGTGATGCATGCATGTAGTCCC AAATACTTAGGAGGCTGAGGTGGAAGGATCACTTGAGCCCAGGAGGTCAAGGCAACAGTGAGCTGTGAT CATGCCACTGCACTCCAGTCTGGGTGACACAGTGAGACCCTGTCTCTTAAAAAAAAAAAAAGAAAGAAA AAAAATTATTCTTTAGGTAATTTCACTTGGACATATTCATGTATATGGAGTTTGTCAGCTGACTCAGGC ATTTACCCTAAAGATCAAATCTGTTTTCAAAAATTGGCATTGGCCAGGCACGGTGACCCACACCTGTAA TCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGGGTTCAAGACCAGCCTGGCCAACA TAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCATGGTGGTGGGCGCCTGTAATCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004157.4
Synonyms	PKR2; PRKAR2
Summary	cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008]
Locus ID	5576
MW	74.3

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