TLR2 (NM_003264) Human 3' UTR Clone

Specifications

Product Data
Product Name	TLR2 (NM_003264) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD282; TIL4
ACCN	NM_003264
Insert Size	1028 bp
Sequence Data	Insert Sequence (showhide) >SC210390 3’UTR clone of NM_003264 The sequence shown below is from the reference sequence of NM_003264. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTAAATCTGAGAGCTGCGATAAAGTCCTAGGTTCCCATATTTAAGACCAGTCTTTGTCTAGTTGGGATC TTTATGTCACTAGTTATAGTTAAGTTCATTCAGACATAATTATATAAAAACTACGTGGATGTACCGTCA TTTGAGGACTTGCTTACTAAAACTACAAAACTTCAAATTTTGTCTGGGGTGCTGTTTTATAAACATATG CCAGATTTAAAAATTGGTTTTTGGTTTTTCTTTTTTCTATGAGATAACCATGATCATAAGTCTATTACT GATATCTGAATATAGTCCCTTGGTATCCAAGGGAATTGGTTGCAGGATCCTCGTGGATATCAAAATTCA TAGATGATCAAGTCCCTTATAAGAGTGGCATAGTATTTGCATATAACCTGTGTACATTCTCCTGTATAC TTTAAATCATCTCTAGATTACTTATGATACCCAATACAATGTAAATACTATGTAAATAGTTGTACTGTC TTTTTATTTATATTATTATTGTTATTTTTTATTTTCAAAATTTTTAAAACATACTTTTGATCCACAGTT GGTTGACTTCATGGATGCAGAACCCATGGATATAGAGGGCCAACTGTAATCTGTAGCAACTGGCTTAGT TCATTAGGAAACAGCACAAATGAACTTAAGATTCTCAATGACTGTGTCATTCTTTCTTCCTGCTAAGAG ACTCCTCTGTGGCCACAAAAGGCATTCTCTGTCCTACCTAGCTGTCACTTCTCTGTGCAGCTGATCTCA AGAGCAACAAGGCAAAGTATTTGGGGCACTCCCCAAAACTTGTTGCTATTCCTAGAAAAAAGTGCTGTG TATTTCCTATTAAACTTTACAGGATGAGAAATACTAGAGGGTGTATTTTCATGTGATCTGGATCTGTCT TTCTGGCTATTAGATAGGTTTCTCCAGCCATAGTTACTTGAGAGAGTGAGTACACAGTGCAAGGTACAG TAAATTATGTATTTCTGTAATTTAACAAAATAAATACTCAGTTTAGGAGAATTTGAAAGACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003264.5
Synonyms	CD282; TIL4
Summary	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Locus ID	7097
MW	39.5

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