SECISBP2 (NM_024077) Human 3' UTR Clone

Specifications

Product Data
Product Name	SECISBP2 (NM_024077) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SBP2
ACCN	NM_024077
Insert Size	869 bp
Sequence Data	Insert Sequence (showhide) >SC210278 3’UTR clone of NM_024077 The sequence shown below is from the reference sequence of NM_024077. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCTCTCAAATGATGAATTTGAATTTATGAGAGTTCTTGCCTGTGTGTCTGTATTTTGGGTAAGGAGGG GAGGTCTGAAAAAGACTTTGGGGCTTTTTCTTCTGTTTTTCATGACAATGTAATTTGTGTAACTGTTGA ATCTGGAAATTGATCAGCATTAAAGGGCACATGAAGCAGTGTCTGCAGGCGTTCAGTGCTGCGGAGCCT GTTAAAGGTCACTCAGATGTGCAGGTGTTAATCTTCTCTAAAAGCCTGGTGATACAGCTCTGGCTTTCT GAGCACACTACGGATCTGGAAAATACTGGAAAATGTGATACTTAGAATACTTTGGCTGCTAAGGAAACT TCCTCTCCATTGCAGAATAGCTGAGCCAAGTGAGTGAGTTTGCAGAAAGCAGGTGGTGAGCTCCTGCCT GCTGGAGGTTGCCATGGAGGGCCATTCCTGCCCGGCAACAGCACCGTCCTGCAGGGAGCCACTTGGCAG AAGGGTGCAGGGCTGCTGGTGTCAGAGCAAGAGGGCTACAGGGAAAGGGCCCTTTCTCAGGGGATGTAG CTTTTTTAAAAGATTTGGGAACACTTGGAGGATTTGCTAAAATGAGCCTCAGAAGGAAAATTGGTTTTC TAACCTGTGACTTTTTGAAATGAATTATTCCTTTCAGTCTTTATTTTTCAAAGAAACAATGTGTATTGA AGTACCTAGATTTGTTTGATAATCAACAAATCTTTCCTTTTTCAATGAACATATTCTGAATGTGGTTTC TGTCTTAGACCAGGAGGACAGAGTTTGCTTTCATATTTTCCCTGTAAGTAAGAGGGCTTATTTATTTTA AATAAAGAGTAATTATTAAATTTTGTTTCAGACTCTGGTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_024077.5
Synonyms	SBP2
Summary	The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Locus ID	79048
MW	32.2

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