FPRL1 (FPR2) (NM_001005738) Human 3' UTR Clone

Specifications

Product Data
Product Name	FPRL1 (FPR2) (NM_001005738) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALXR; FMLP-R-II; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
ACCN	NM_001005738
Insert Size	847 bp
Sequence Data	Insert Sequence (showhide) >SC210162 3’UTR clone of NM_001005738 The sequence shown below is from the reference sequence of NM_001005738. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTGCAGAGACTGAGTTACAGGCAATGTGAGGATGGGGTCAGGGATATTTTGAGTTCTGTTCATCCTAC CCTAATGCCAGTTCCAGCTTCATCTACCCTTGAGTCATATTGAGGCATTCAAGGATGCACAGCTCAAGT ATTTATTCAGGAAAAATGCTTTTGTGTCCCTGATTTGGGGCTAAGAAATAGACAGTCAGGCTACTAAAA TATTAGTGTTATTTTTTGTTTTTTGACTTCTGCCTATACCCTGGGGTAAGTGGAGTTGGGAAATACAAG AAGAGAAAGACCAGTGGGGATTTGTAAGACTTAGATGAGATAGCGCATAATAAGGGGAAGACTTTAAAG TATAAAGTAAAATGTTTGCTGTAGGTTTTTTATAGCTATTAAAAAAAATCAGATTATGGAAGTTTTCTT CTATTTTTAGTTTGCTAAGAGTTTTCTGTTTCTTTTTCTTACATCATGAGTGGACTTTGCATTTTATCA AATGCATTTTCTACATGTATTAAGATGGTCATATTATTCTTCTTCTTTTATGTAAATCATTATAAATAA TGTTCATTAAGTTCTGAATGTTAAACTACTCTTGAATTCCTGGAATAAACCACACTTAGTCCTGATGTA CTTTAAATATTTATATCTCACAGGAGTTGGTTAGAATTTCTGTGTTTATGTTTATATACTGTTATTTCA CTTTTTCTACTATCCTTGCTAAGTTTTCATAGAAAATAAGGAACAAAGAGAAACTTGTAATGGTCTCTG AAAAGGAATTGAGAAGTAATTCCTCTGATTCTGTTTTCTGGTGTTATATCTTTATTAAATATTCAGAAA AATTCACCAGTGAAGCCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001005738.2
Synonyms	ALXR; FMLP-R-II; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
Summary	Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1374236). The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4) (PubMed:9547339). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	2358
MW	32.5

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