IL12RB2 (NM_001559) Human 3' UTR Clone

Specifications

Product Data
Product Name	IL12RB2 (NM_001559) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_001559
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC210087 3’UTR clone of NM_001559 The sequence shown below is from the reference sequence of NM_001559. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGATGAGGTGTGACTCCCTCATGCTCTGAGTGGTGAGGCTTCAAGCCTTAAAGTCAGTGTGCCCTCAA CCAGCACAGCCTGCCCCAATTCCCCCAGCCCCTGCTCCAGCAGCTGTCATCTCTGGGTGCCACCATCGG TCTGGCTGCAGCTAGAGGACAGGCAAGCCAGCTCTGGGGGAGTCTTAGGAACTGGGAGTTGGTCTTCAC TCAGATGCCTCATCTTGCCTTTCCCAGGGCCTTAAAATTACATCCTTCACTGTGTGGACCTAGAGACTC CAACTTGAATTCCTAGTAACTTTCTTGGTATGCTGGCCAGAAAGGGAAATGAGGAGGAGAGTAGAAACC ACAGCTCTTAGTAGTAATGGCATACAGTCTAGAGGACCATTCATGCAATGACTATTTCTAAAGCACCTG CTACACAGCAGGCTGTACACAGCAGATCAGTACTGTTCAACAGAACTTCCTGAGATGATGGAAATGTTC TACCTCTGCACTCACTGTCCAGTACATTAGACACTAGGCACATTGGCTGTTAATCACTTGGAATGTGTT TAGCTTGACTGAGGAATTAAATTTTGATTGTAAATTTAAATCGCCACACATGGCTAGTGGCTACTGTAT TGGAGTGCACAGCTCTAGATGGCTCCTAGATTATTGAGAGCCTTCAAAACAAATCAACCTAGTTCTATA GATGAAGACATAAAAGACACTGGTAAACACCAAGGTAAAAGGGCCCCCAAGGTGGTCATGACTGGTCTC ATTTGCAGAAGTCTAAGAATGTACCTTTTTCTGGCCGGGCGTGGTAGCTCATGCCTGTAATCCCAGCAC TTTGGGAGGCTGAGGCAGGCGGATCATGAGGTCAGGAGATCGAGACCATTCTGGCTAACATGGTGAAAC CCCATCTCTACTAAAAATATTTTTAAAAAAAATTAACTGGGCGTGATGGCGGGCGCCTGTAGTCCCAGC TACTCGGGAGGCTGAGGGAGGAGAATGACATGAACCTGGGAGGTGGGGCTTGCAGTGAGCCACTGCACT CCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAGAAAAAAAAAAAAAAGAATGTACCTTTTTCC TAGATTTGCTGGTTTATTGTTTTATTTTGGCTTCATCCTCTTTCAGCAAATCAAGGGCAGCTGGATGGT GAAGACCTATATTGTAAACTCACCATAGTACCATAGTACCTTGGGCAACCCAGCCTCCCACTCTGAATC TCGGGTGTCTTGTAAAGGGCTGGACCAAAGGCTCCCTGACCCCTTGTTTCCTCTCCTTTTTGCTGCAGC AGGCCCTGCCTTCAGGACCAGGGCTGTCTCAGGGTCTAAGACCCCAACCTCTGAGGTTGTCCTCAGAAG TGGTCTGTCCCCTGTTCCCAAAGGCACAGCTTTCATTCCCGGAGAAGATATTGAGCTGGTCCTCTGCCA GCTCAAGTTGAGCCTGGAAGATAACTCTCTTTTCCACAACATGGACTTGGAACATGATCCATGTTTTGC TCTTTAAAGCTGTGGCCCCTGGCTTGCCACCCTCCCTAGCCCATTGCTGCCTCTGTCTCTTCACCATAG GCACTTCTGCCAAACTAGTGGAGAAGTCTTGGTCTAAACTGCTAATAATGCTCTTCCCTAAAGAACAGG ATAAAAGATCCAAAATACTTTTTCTTAAATTCCTGTCAAGCCTGGGGTCCACCCCGTACCCCTTCCCAC ATGAACGCTGGAACTGAGATGGCTTCCCCATCATCGTCTGGATTTTCATTTAACAAAGTACTTGTTGTA AATGTGTACTTCTTGCCTAACGTGAGGAACTAAAAACTTGTCCATGCATACCCCAGTCCTGTAGAAATA ACTGTTCTCGGGCTTTAGGTTTTCCAGATTTCCCTCAGAGCTCTAGAAACTGAGCGATGGACAGTTGCT CTGCTTCTTCAGGTTGGAACTCTTGATACATCCTTGTTTCCTGAAATTCCAAACTTAACACCTATAGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001559.3
Summary	The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
Locus ID	3595
MW	74.2

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