RIC8 (RIC8A) (NM_021932) Human 3' UTR Clone

Specifications

Product Data
Product Name	RIC8 (RIC8A) (NM_021932) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	RIC8
ACCN	NM_021932
Insert Size	793 bp
Sequence Data	Insert Sequence (showhide) >SC209765 3’UTR clone of NM_021932 The sequence shown below is from the reference sequence of NM_021932. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCTCGGACCCTGACTCGGACCCTGACTGAGGATGGCAGCTCTTCTGCTCCCCCATCAGGACTGGTGCT GCTTCCAGAGACTTCCTTGGGGTTGCAACCTGGGGAAGCCACATCCCACTGGATCCACACCCGCCCCCA CTTCTCCATCTTAGAAACCCCTTCTCTTGACTCCCGTTCTGTTCATGATTTGCCTCTGGTCCAGTTTCT CATCTCTGGACTGCAACGGTCTTCTTGTGCTAGAACTCAGGCTCAGCCTCGAATTCCACAGACGAAGTA CTTTCTTTTGTCTGCGCCAAGAGGAATGTGTTCAGAAGCTGCTGCCTGAGGGCAGGGCCTACCTGGGCA CACAGAAGAGCATATGGGAGGGCAGGGGTTTGGGTGTGGGTGCACACAAAGCAAGCACCATCTGGGATT GGCACACTGGCAGAGCCAGTGTGTTGGGGTATGTGCTGCACTTCCCAGGGAGAAAACCTGTCAGAACTT TCCATACGAGTATATCAGAACACACCCTTCCAAGGTATGTATGCTCTGTTGTTCCTGTCCTGTCTTCAC TGAGCGCAGGGCTGGAGGCCTCTTAGACATTCTCCTTGGTCCTCGTTCAGCTGCCCACTGTAGTATCCA CAGTGCCCGAGTTCTCGCTGGTTTTGGCAATTAAACCTCCTTCCTACTGGTTTAGACTACACTTACAAC AAGGAAAATGCCCCTCGTGTGACCATAGATTGAGATTTATACCACATACCACACATAGCCACAGAAACA TCATCTTGAAATAAAGAAGAGTTTTGGACAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_021932.6
Synonyms	RIC8
Summary	Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.[UniProtKB/Swiss-Prot Function]
Locus ID	60626
MW	29.6

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