PKC gamma (PRKCG) (NM_002739) Human 3' UTR Clone

Specifications

Product Data
Product Name	PKC gamma (PRKCG) (NM_002739) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PKC-gamma; PKCC; PKCG; PKCgamma; PKCI(3); SCA14
ACCN	NM_002739
Insert Size	787 bp
Sequence Data	Insert Sequence (showhide) >SC209698 3’UTR clone of NM_002739 The sequence shown below is from the reference sequence of NM_002739. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCAGCCCAGTGCCTGTGCCCGTCATGTAATCTCACCCGCCGCCACTAGGTGTCCCCAACGTCCCCTCC GCCGTGCCGGCGGCAGCCCCACTTCACCCCCAACTTCACCACCCCCTGTCCCATTCTAGATCCTGCACC CCAGCATTCCAGCTCTGCCCCCGCGGGTTCTAGACGCCCCTCCCAAGCGTTCCTGGCCTTCTGAACTCC ATACAGCCTCTACAGCCGTCCCGCGTTCAAGACTTGAGCGGAGCCCGATATTCTCCCTGACCTTAGCGT TCTGGACTCTGCCCCAATCGGGTCCAGAGACCACACCACTAACCATCCCCAACTCCATGGGGTTCGAGA CTCCATCTTGGTAGTTCTGTGCCTCCCCCCAGACCCCGCCCCTGGGGAAATAGCCTCACGGGGTTGGCT GTTCCAGACTCAGGTTCCAGAACAGCCCTCGGCCTCCGAGGCTCCCCGCCTCCACTCTAGTTCTAGATG AGTGGGAGGCGTGCCCCCCTCCTCCAGTACGTCCCGCTGCTGTGCTCTGGGGATTTCTGGGATATATGG AGGATTCTTTCCCCAGAGGCTCCCAATCAGCTTTTGTTCTAGACTTCCCCATCCCGAAGCCATCACTTC TCCCCGCAGCCCGCCTGCCGTGCATGGCTCCTGTCTGGCTCGGACCCACCCCAACTCTCCCCAGTGCCT GCCACTCTCTGGGACTCTCCTCCTCCCCTCCTCTTCCCTTAGCCTCTCCCACCCGGCCACAGCTGCTGG AGAATAAATTTGGGATGCTGATGCTGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002739.5
Synonyms	PKC-gamma; PKCC; PKCG; PKCgamma; PKCI(3); SCA14
Summary	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Locus ID	5582
MW	28.2

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