APH1A (NM_001077628) Human 3' UTR Clone
CAT#: SC209576
3' UTR clone of anterior pharynx defective 1 homolog A (C. elegans) (APH1A) transcript variant 1 for miRNA target validation
Need custom modification / cloning service?
Get a free quote
CNY 4,845.00
货期*
3周
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Product Name | APH1A (NM_001077628) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | 6530402N02Rik; APH-1; APH-1A; CGI-78 |
ACCN | NM_001077628 |
Insert Size | 756 bp |
Sequence Data |
>SC209576 3’UTR clone of NM_001077628
The sequence shown below is from the reference sequence of NM_001077628. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCTGCCCTGCGCATCCCACCCGAGGACTGAGGGAACCTAGGGGGGACCCCTGGGCCTGGGGTGCCCTCC TGATGTCCTCGCCCTGTATTTCTCCATCTCCAGTTCTGGACAGTGCAGGTTGCCAAGAAAAGGGACCTA GTTTAGCCATTGCCCTGGAGATGAAATTAATGGAGGCTCAAGGATAGATGAGCTCTGAGTTTCTCAGTA CTCCCTCAAGACTGGACATCTTGGTCTTTTTCTCAGGCCTGAGGGGGAACCATTTTTGGTGTGATAAAT ACCCTAAACTGCCTTTTTTTCTTTTTTGAGGTGGGGGGAGGGAGGAGGTATATTGGAACTCTTCTAACC TCCTTGGGCTATATTTTCTCTCCTCGAGTTGCTCCTCATGGCTGGGCTCATTTCGGTCCCTTTCTCCTT GGTCCCAGACCTTGGGGGAAAGGAAGGAAGTGCATGTTTGGGAACTGGCATTACTGGAACTAATGGTTT TAACCTCCTTAACCACCAGCATCCCTCCTCTCCCCAAGGTGAAGTGGAGGGTGCTGTGGTGAGCTGGCC ACTCCAGAGCTGCAGTGCCACTGGAGGAGTCAGACTACCATGACATCGTAGGGAAGGAGGGGAGATTTT TTTGTAGTTTTTAATTGGGGTGTGGGAGGGGCGGGGAGGTTTTCTATAAACTGTATCATTTTCTGCTGA GGGTGGAGTGTCCCATCCTTTTAATCAAGGTGATTGTGATTTTGACTAATAAAAAAGAATTTGTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001077628.3 |
Synonyms | 6530402N02Rik; APH-1; APH-1A; CGI-78 |
Summary | This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants. [provided by RefSeq, Aug 2011] |
Locus ID | 51107 |
MW | 28.3 |
Documents
Product Manuals |
FAQs |
Resources
Customer
Reviews
Loading...