FEN1 (NM_004111) Human 3' UTR Clone

Specifications

Product Data
Product Name	FEN1 (NM_004111) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FEN-1; MF1; RAD2
ACCN	NM_004111
Insert Size	764 bp
Sequence Data	Insert Sequence (showhide) >SC209529 3’UTR clone of NM_004111 The sequence shown below is from the reference sequence of NM_004111. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCAGCAGGGAAGTTTAAAAGGGGAAAATAAATGTGTTTCCCCATTATACCTCCTTCACCCCAGAATATT TGCCGTCTTGTACCCTTAAGAGCTACAGCTAGAGAAACCTTCACGGGGTGGAGAGAGGATTCTAAGGCT TTTCTAGCGTGACCCTTTTCAGTAGTGCTAGTCCCTTTTTTACTTGATCTTAATGGCAAGAAGGCCACA GAGGTACTTTTCCTTTTTTAGCTCAGGAAAATATGTCAGGCTCAAACCACTTCTCAGGCAGTTTAATGG ACACTAAGTCCATTGTTACATGAAAGTGATAGATAGCAACAAGTTTTGGAGAAGAGAGAGGGAGATAAA AGGGGGAGACAAAAGATGTACAGAAATGATTTCCTGGCTGGCCAACTGGTGGCCAGTGGGAGGTGATGG TGGACCTAGACTGTGCTTTTCTGTCTTGTTCAGCCTTGACCCACCTTGAGAGAGAGCCACCAGGAAGGC GCATCTTAGCAGATGGGAGGAACTGCTGAGAGAAGATGGGCAGAAAGCTGGAGCCCCTGGAGTTGGCTG TGTCTGTGTTTGTGACTGATTACTGGCTGTGTCTTGGGTGGGCAGAAACTCGAACTTGCTATGTAATTT GTGTCTAGTTATTCAGAGGAGTAAGATGGTGATGTTCACCTGGCAATCAGCTGAGTTGAGACTTTGGAA TAAGACACTGGTTTTCATGCGCTGTTTTTGTTTTAAAGTTATGAAGAAAAAAGTCAATAAAATTCTAAA AGTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004111.6
Synonyms	FEN-1; MF1; RAD2
Summary	The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008]
Locus ID	2237
MW	28.8

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.