S100 beta (S100B) (NM_006272) Human 3' UTR Clone

Specifications

Product Data
Product Name	S100 beta (S100B) (NM_006272) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	NEF; S100; S100-B; S100beta
ACCN	NM_006272
Insert Size	789 bp
Sequence Data	Insert Sequence (showhide) >SC209492 3’UTR clone of NM_006272 The sequence shown below is from the reference sequence of NM_006272. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCCTGCCACGAGTTCTTTGAACATGAGTGAGATTAGAAAGCAGCCAAACCTTTCCTGTAACAGAGACGG TCATGCAAGAAAGCAGACAGCAAGGGCTTGCAGCCTAGTAGGAGCTGAGCTTTCCAGCCGTGTTGTAGC TAATTAGGAAGCTTGATTTGCTTTGTGATTGAAAAATTGAAAACCTCTTTCCAAAGGCTGTTTTAACGG CCTGCATCATTCTTTCTGCTATATTAGGCCTGTGTGTAAGCTGACTGGCCCCAGGGACTCTTGTTAACA GTAACTTAGGAGTCAGGTCTCAGTGATAAAGCGTGCACCGTGCAGCCCGCCATGGCCGTGTAGACCCTA ACCCGGAGGGAACCCTGACTACAGAAATTACCCCGGGGCACCCTTAAAACTTCCACTACCTTTAAAAAA CAAAGCCTTATCCAGCATTATTTGAAAACACTGCTGTTCTTTAAATGCGTTCCTCATCCATGCAGATAA CAGCTGGTTGGCCGGTGTGGCCCTGCAAGGGCGTGGTGGCTTCGGCCTGCTTCCCGGGATGCGCCTGAT CACCAGGTGAACGCTCAGCGCTGGCAGCGCTCCTGGAAAAAGCAACTCCATCAGAACTCGCAATCCGAG CCAGCTCTGGGGGCTCCAGCGTGGCCTCCGTGACCCATGCGATTCAAGTCGCGGCTGCAGGATCCTTGC CTCCAACGTGCCTCCAGCACATGCGGCTTCCGAGGGCACTACCGGGGGCTCTGAGCCACCGCGAGGGCC TGCGTTCAATAAAAAGAGCGCAGCTTGGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006272.3
Synonyms	NEF; S100; S100-B; S100beta
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
Locus ID	6285
MW	29.9

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