p57 Kip2 (CDKN1C) (NM_001122630) Human 3' UTR Clone

Specifications

Product Data
Product Name	p57 Kip2 (CDKN1C) (NM_001122630) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BWCR; BWS; KIP2; p57; p57Kip2; WBS
ACCN	NM_001122630
Insert Size	733 bp
Sequence Data	Insert Sequence (showhide) >SC209218 3’UTR clone of NM_001122630 The sequence shown below is from the reference sequence of NM_001122630. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGCAGACCCCGCGCAAGAGGCTGCGGTGAGCCAATTTAGAGCCCAAAGAGCCCCGAGGGAACCTGCCG GGGCAGCGGACGTTGGAAGGGCGCTGGGCCTCGGCTGGGACCGTTCATGTAGCAGCAACCGGCGGCGGC TGCCGCAGAGCAGCGTTCGGTTTTGTTTTTAAATTTTGAAAACTGTGCAATGTATTAATAACGTCTTTT TATATCTAAATGTATTCTGCACGAGAAGGTACACTGGTCCCAAGGTGTAAAGCTTTAAGAGTCATTTAT ATAAAATGTTTAATCTCTGCTGAAACTCAGTGCAAAAAAAAGAAAAAAGAAAAAAAAAAGGAAAAAATA AAAAAACCATGTATATTTGTACAAAAAGTTTTTAAAGTTATACTAACTTATATTTTCTATTTATGTCCA GGCGTGGACCGCTCTGCCACGCACTAGCTCGGTTATTGGTTATGCCAAAGGCACTCTCCATCTCCCACA TCTGGTTATTGACAAGTGTAACTTTATTTTCATCGCGGACTCTGGGGAAGGGGGTCACTCACAAGCTGT AGCTGCCATACATGCCCATCTAGCTTGCAGTCTCTTCGCGCTTTCGCTGTCTCTCTTATTATGACTGTG TTTATCTGAAACTTGAAGACAAGTCTGTTAAAATGGTTCCTGAGCCGTCTGTACCACTGCCCCGGCCCC TCGTCCGCCGGGTTCTAAATAAAGAGGCCGAAAAATGCTGCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001122630.2
Synonyms	BWCR; BWS; KIP2; p57; p57Kip2; WBS
Summary	This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Locus ID	1028
MW	27.6

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