ALS2CR2 (STRADB) (NM_018571) Human 3' UTR Clone

Specifications

Product Data
Product Name	ALS2CR2 (STRADB) (NM_018571) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALS2CR2; CALS-21; ILPIP; ILPIPA; PAPK; PRO1038
ACCN	NM_018571
Insert Size	701 bp
Sequence Data	Insert Sequence (showhide) >SC208823 3’UTR clone of NM_018571 The sequence shown below is from the reference sequence of NM_018571. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GATGAAAAAGACTCATACTGGGAATTCTAGGGCTGCCAAATCATTTTATGTCCTATATACTTGACACTT TCTCCTTGCTGCTTTTTCTTCTGTATTTCTAGGTACAAATACCAGAATTATACTTGAAAATACAGTTGG TGCACTGGAGAATCTATTATTTAAAACCACTCTGTTCAAAGGGGCACCAGTTTGTAGTCCCTCTGTTTC GCACAGAGTACTATGACAAGGAAACATCAGAATTACTAATCTAGCTAGTGTCATTTATTCTGGAATTTT TTTCTAAGCTGTGACTAACTCTTTTTATCTCTCAATATAATTTTTGAGCCAGTTAATTTTTTTCAGTAT TTTGCTGTCCCTTGGGAATGGGCCCTCAGAGGACAGTGCTTCCAAGTACATCTTCTCCCAGATTCTCTG GCCTTTTTAATGAGCTATTGTTAAACCAACAGGCTAGTTTATCTTACATCAGACCCTTTTCTGGTAGAG GGAAAATGTTTGTGCTTTCCCTTTTTCTTCTGTTAATACTTATGGTAACACCTAACTGAGCCTCACTCA CATTAAATGATTCACTTGAAATATATACAGAAATTGTAATTTGCTTTTTTTTAAACAAGGGGGCTAAAG TAACACTTTCCTACTTATGTAAATTATAGATCCTAAATTCACGCACCCCGTGGGAGCTCAATAAAGATT TACTGAATTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_018571.6
Synonyms	ALS2CR2; CALS-21; ILPIP; ILPIPA; PAPK; PRO1038
Summary	This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Locus ID	55437
MW	27.8

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