Annexin VII (ANXA7) (NM_004034) Human 3' UTR Clone

Specifications

Product Data
Product Name	Annexin VII (ANXA7) (NM_004034) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ANX7; SNX; SYNEXIN
ACCN	NM_004034
Insert Size	1024 bp
Sequence Data	Insert Sequence (showhide) >SC208745 3’UTR clone of NM_004034 The sequence shown below is from the reference sequence of NM_004034. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGACTTCTTCTGGCTATTGTGGGCCAGTAGGAGGGATTTTTTTTTTTTTAATGAAAAAAAATTTCTATT CATAGCTTATCCTTCAGAGCAATGACCTGCATGCAGCAATATCAAACATCAGCTAACCGAAAGAGCTTT CTGTCAAGGACCGTATCAGGGTAATGTGCTTGGTTTGCACATGTTGTTATTGCCTTAATTCTAATTTTA TTTTGTTCTCTACATACAATCAATGTAAAGCCATATCACAATGATACAGTAATATTGCAATGTTTGTAA ACCTTCATTCTTACTAGTTTCATTCTAATCAAGATGTCAAATTGAATAAAAATCACAGCAATCTCTGAT TCTGTGTAATAATATTGAATAATTTTTTAGAAGGTTACTGAAAGCTCTGCCTTCCGGAATCCCTCTAAG TCTGCTTGATAGAGTGGATAGTGTGTTAAAACTGTGTACTTTAAAAAAAAATTCAACCTTTACATCTAG AATAATTTGCATCTCATTTTGCCTAAATTGGTTCTGTATTCATAAACACTTTCCACATAGAAAATAGAT TAGTATTACCTGTGGCACCTTTTAAGAAAGGGTCAAATGTTTATATGCTTAAGATACATAGCCTACTTT TTTTTCGCAGTTGTTTTCTTTTTTTAAATTGAGTTATGACAAATAAAAAATTGCATATATTTAAGGTGT ACAATATGGTGTTTTGATATCAGCATTCCTTGTGTAATGATTCCACAATTAAGGTCAGGCTAATTACGT ATCTGTCACCTTGACATAGTTACCATTTTTTCATGTGTGGTGAAAACACTTAAGATCTACTACCTTAGC AAATTTTAAGTGTTCAGTACATTATTAACTATAGATACTGTGCTCTACATTAAACCTCTAGCATTTATT CGTTTTATAACTGAAAGTTTATACCCTTTGACCAACATCTCCCCATTTTCCCCACCTCTCACCTGGACA ACCACCACTGTGTTTAAGTTCAGCTATTTTAGATTCCACGTATAAATGGTATACAATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004034.4
Synonyms	ANX7; SNX; SYNEXIN
Summary	Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
Locus ID	310
MW	39.8

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