ADAMTS8 (NM_007037) Human 3' UTR Clone

Specifications

Product Data
Product Name	ADAMTS8 (NM_007037) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ADAM-TS8; METH2
ACCN	NM_007037
Insert Size	665 bp
Sequence Data	Insert Sequence (showhide) >SC208497 3’UTR clone of NM_007037 The sequence shown below is from the reference sequence of NM_007037. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCTGCGAAAGCCAGCTGTGCCCCCTGTGATTCAGGGGGGCAGGGGCCAGTCTTGTGCTCCTGGACATG CGGTACTGAGGTGCAGACAAGGGTCTCCACTGTGGTGACTGGGTCCCTTGGCCATATCAAGGCAGCACG GCCCACCCAGGCCTCCCATTGCCGCAACCCCTCCAGTACTGCACAAATTCCTAAGGGGGAAGAGGAGAG GGTATGGGGCGGCAGACCCTATCATCAACTGTCCAGTGGACTGGACCTTGCTCGGGTTCAAGTAGAGGG CATAGGTTAAAAGGTAAAAGTGCACTTATTGACTCAGACAGGACACTCAGCGTCAGTCTGTTTGCAAAG GACTAGCAAACTTAAATGAAAAAAAAAATTCTATCTGGTTTCCCCGATAAATAATCTACCTCACAGGGG AAAAAATTAGTACAAGAGAGGCGTGGGGCAGGGAGTCAATGGTGAATGTCAAAGCAGGCTCCAAAGCTG GACCCCAAGCTGTCTTCAAGAATGACCACGACTGTCTTCAGTGTTAAAATCCATCACCTAAAGGGCCGC AGCGTCGCAGGGTTTGGAGAGCCACATGTTCTCAGGCTGCCACCTGCAGGGGTGGATCCATTTCAAGTA TTTATGCAAATGTGTCTCTGAACTAAAGTGTGATCTTATGCCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_007037.6
Synonyms	ADAM-TS8; METH2
Summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016]
Locus ID	11095
MW	24.1

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