HEXA (NM_000520) Human 3' UTR Clone

Specifications

Product Data
Product Name	HEXA (NM_000520) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	TSD
ACCN	NM_000520
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC208386 3’UTR clone of NM_000520 The sequence shown below is from the reference sequence of NM_000520. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTCTGTGAGCAGGAGTTTGAACAGACCTGAGCCCCAGGCACCGAGGAGGGTGCTGGCTGTAGGTGAATG GTAGTGGAGCCAGGCTTCCACTGCATCCTGGCCAGGGGACGGAGCCCCTTGCCTTCGTGCCCCTTGCCT GCGTGCCCCTGTGCTTGGAGAGAAAGGGGCCGGTGCTGGCGCTCGCATTCAATAAAGAGTAATGTGGCA TTTTTCTATAATAAACATGGATTACCTGTGTTTAAAAAAAAAAGTGTGAATGGCGTTAGGGTAAGGGCA CAGCCAGGCTGGAGTCAGTGTCTGCCCCTGAGGTCTTTTAAGTTGAGGGCTGGGAATGAAACCTATAGC CTTTGTGCTGTTCTGCCTTGCCTGTGAGCTATGTCACTCCCCTCCCACTCCTGACCATATTCCAGACAC CTGCCCTAATCCTCAGCCTGCTCACTTCACTTCTGCATTATATCTCCAAGGCGTTGGTATATGGAAAAA GATGTAGGGGCTTGGAGGTGTTCTGGACAGTGGGGAGGGCTCCAGACCCAACCTGGTCACAGAAGAGCC TCTCCCCCATGCATACTCATCCACCTCCCTCCCCTAGAGCTATTCTCCTTTGGGTTTCTTGCTGCTTCA ATTTTATACAACCATTATTTAAATATTATTAAACACATATTGTTCTCTAGGCACTGTGGTAGTGGGTTT TTTTGTTGTTTTTGTTTTTGAGACTGTCTCAAAAACTCTGTCGCCCAGGCTGACAGTGCAGTGGCACAA TCTTGGCTCACTGCAGCCTCTGCCTCCTGGGTTCAAGCGATTCTCGTGCATCAGCCTCCTGAGTAACTG GAATTAATAGGCACGTGCCACCATGTCCATCTAATTCATATATATATATTTTTTTTTTCTGAGACGGAG TCTCACTGTCACACAGGCTGGAGTGCAGTGGCACGATCTCGACTCACTGCAAGCTCCACCTCCTGGGTT CACGCCATTCTCCTGCCTCAGCCTCCCCAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCGGCTAA TTTTTTGTATTTTTAGTAGAGATGGGGTTTCTCCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCG TGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCGAATTC ATCTATTTTTAGTAGAGATGGGGTTTCACTATATTGGCCAGGCTGGTCTTGAACTCATGACCTCAGATG TTCACTTGTCTTGGCCTCCCAAAGTGCTGGGATTAGAGGCGTGAGCCACCGCACGCGGGCCTGTGGTAA ATTGTTGAATTTGAAGGACTCAGAGGCCCTGGTCAATTCCAAAATAACGTAGGCGACTTCCATCCCCCT CCTCCCAACCATTTTCAGCCCAAAGCATCTTCGCAGGGAATGGATGGCTGCGCGGAGGTGGGCGGTGGC TCTGGAGAGGGTCTTTGCAGGTGTGATTTTCTCTAGAAGGAAATGTCTCGTCGTGGACCCAGACTGCCC CCTCCTGGTTTCAGATGCAGAAGTGATACTGTAAGCCAGAGGCGGGGGCAGTAATGCATCGCAGCCATT TTAGGTGAGGATTTCCTTGGCGGTTATTTGTTAAGTTCTTTGGCTGGGCCCTGGGCTGGGGTAACAATG GACAGGTTCCAGGCATTTTTTTCAGAAAGCTTCCAGTGTAGTGGATACAGAAACTTCAGGAAGGCAGGG CTGAGAAGGATCTGAGTAAAACTCGGTCCTTCAACACCATCCTTCAGCCCCTGGGTCATGTTCCTTCGA GGTCCTGGTGGGAGGTAGACAAGCCTAGCCTTGTGCTGTTCCTGTAAGGACAGGGTGGGCATTTTCTAC CAACAGAATTCTTGGAATTTTCACACAGCCCAGCCTAGCCAAGTCCAGGGCTATAGCCCAGATACACAA GTTAAGGTCCCAGCACTGGCACCCACCACAGGAGCCCCCTTACCTCTATTACCCAGAAGCTTGTAGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000520.6
Synonyms	TSD
Summary	This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Locus ID	3073
MW	74

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