HERPUD1 (NM_001010989) Human 3' UTR Clone

Specifications

Product Data
Product Name	HERPUD1 (NM_001010989) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HERP; Mif1; SUP
ACCN	NM_001010989
Insert Size	1604 bp
Sequence Data	Insert Sequence (showhide) >SC208111 3’UTR clone of NM_001010989 The sequence shown below is from the reference sequence of NM_001010989. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCAGAAGGCCCCCCAGCCATCGCAAACTGATGGTGTTTGTGCTGTAGCTGTTGGAGGCTTTGACAGGAA TGGACTGGATCACCTGACTCCAGCTAGATTGCCTCTCCTGGACATGGCAATGATGAGTTTTTAAAAAAC AGTGTGGATGATGATATGCTTTTGTGAGCAAGCAAAAGCAGAAACGTGAAGCCGTGATACAAATTGGTG AACAAAAAATGCCCAAGGCTTCTCATGTCTTTATTCTGAAGAGCTTTAATATATACTCTATGTAGTTTA ATAAGCACTGTACGTAGAAGGCCTTAGGTGTTGCATGTCTATGCTTGAGGAACTTTTCCAAATGTGTGT GTCTGCATGTGTGTTTGTACATAGAAGTCATAGATGCAGAAGTGGTTCTGCTGGTACGATTTGATTCCT GTTGGAATGTTTAAATTACACTAAGTGTACTACTTTATATAATCAATGAAATTGCTAGACATGTTTTAG CAGGACTTTTCTAGGAAAGACTTATGTATAATTGCTTTTTAAAATGCAGTGCTTTACTTTAAACTAAGG GGAACTTTGCGGAGGTGAAAACCTTTGCTGGGTTTTCTGTTCAATAAAGTTTTACTATGAATGACCCTG GCAGAGACTCCTGTCATCCTAGCAGTTTACTCTGCGTTTGTTGTATCTAGACAGTCAACAACTGAGTTG TCGGTGTTTAACCTGAATGCTTGTTTTTCAGAAGAGGACTGTTTGTGCCGGTAAGAATGATCAGGTAAG GCCATGAAAGTTTTTGTTGGCGTTTTTGTTTTTGAGATGGGGTCTTGCTTTGTTCCTTGGGCCAGAGTA CATTGGCTACTCACAAGTGGGCTGGTAGCTGGCTACAGCCCCAGACTCCTGGCTTAAGCCACCTCCTGC CTCAGCCACCCTGGCAGCTGGGACTACAGGCATGCGCCATCACACTTAGCTTGAAAGTTTTAATTTACT AAGAATATACCTGTGTTTCCCCCCATTTCCTGATTTAAACAGTACTGGCTTATATAGGAACCCATCAAA GTTAAATTCCCCAAATTTAAATTTAGTAAATTTAGTGGTTTCACCTTGGCAAATCTGCAATAGTTTCAC CAGCTCAAATTTCATGCTTTTGTAAGCTGAGCTTATGTTTGTGATTTTAATCCTTTAAGTACTACTGTG GTAACTAATCATTTTTTTGTTTTTTTTGGTGGTGTTTTTGTTTTTGTTTTGAGATGGAGTCTCACTCTG TTGCCCAGGCTGGAGTGCCGTGGCGCGATCTCGGCTCACTGCAACCTCTACCTCCTGAGTTCAAGCGAT TCTCCTGCCTCAGCCTCCCGAATAGCTGGGATTACAGGTGCCCACCACAATGTCTGGCTAATTTTTTGT ATTTTTAGTAGAGACGAGGTTTCACCCATGTTGGCCAGGCTGGTCTCAAACCCCTGACCTCAGGTGATC TGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCACCGCACCCAGCCAGGGACTAATC TTTAAAGCAAAGTTTTATATATTTTTACGTGAGTAATGTTATGTGTAGGTGTTCTATTTGGCAAAATAA ATCAGCCTTTTCTATCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001010989.3
Synonyms	HERP; Mif1; SUP
Summary	The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
Locus ID	9709
MW	60.8

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