PON1 (NM_000446) Human 3' UTR Clone

Specifications

Product Data
Product Name	PON1 (NM_000446) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ESA; MVCD5; PON
ACCN	NM_000446
Insert Size	1298 bp
Sequence Data	Insert Sequence (showhide) >SC207986 3’UTR clone of NM_000446 The sequence shown below is from the reference sequence of NM_000446. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTTCACAAAGCTCTTTACTGTGAGCTCTAACAGACCGATTTGCACCCATGCCATAGAAACTGAGGCCAT TATTTCAACCGCTTGCCATATTCCGAGGACCCAGTGTTCTTAGCTGAACAATGAATGCTGACCCTAAAT GTGGACATCATGAAGCATCAAAGCACTGTTTAACTGGGAGTGATATGATGTGTAGGGCTTTTTTTTGAG AATACACTATCAAATCAGTCTTGGAATACTTGAAAACCTCATTTACCATAAAAATCCTTCTCACTAAAA TGGATAAATCAGTTATGTCAATTGTCAGATATTAAATAACAGTGTGTGACCCCAAAAGTACTTACCCTA AAACATGTGTTGCCTGGAAGCACATGTGTGTATCGCTGCCTTGCCATGTCTTGTTCAGAAGACACAGGG GAGCAGGGTTAGCTCACGTGTCTTTAGAACTCCAGTACTCACCCAGGGACTCCAGTTCACAGGCCAGAA AACATATGCATTATGAAGTTCCCCTCTACTCCATGCACATAGTAAGTCTGACTATGGCAGTCAGACTTA CTTACTCCCATTTTCCCTTCGATATATGACTTTTTCTCAGTAAATATTAACCTGAATTATTCCAACTCC CCTTGTACTCTTGCTTTTTCAATTCTCCTGTTGCAATGACACATAGGAAAATCTTAAAATTCTTGGGAG TGTTGTCACACCTGAAAATTATGAGTCTCTATGATCTTGGCACAAATTGTACATTTGAGTGTCTTTGAC TTGGTTAAAGGAAGTTTGTTCACTTCGATGACTGGATACAGAATGAATCCCATAATTGACATGGGCGAA GCTAAAAGTGTCCCCAAAGACTACACTGTTGTTGAGGTGGTGGTAGTGCTGGTGGGTTTTTGTTTAATA TTTAAACTTCTTGTTGTGGAGGCTGAAAAGAAAAAAAATAATAGAAAGGTAAACAAACAAATAAATAGA AAAGATCAACAACCCCTTTGGCTATCTACTGAGACATGACTAGGAAGAAAACATGACTTTATCATTTTG TTATAGAAACTGATATATAAAGGTTACACATTTTCATTTATTTGTTTTTCTGATTTGAAGGTATAACCT TCATGATGAATTACTTCTTCAGGGTGTTAAGGCAGTGACTTTAGAAACAAATTTTTTTCTTGTTTTTGT TTTGTTTTTGAGACCGAATCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTG CAACTTCTACCTCCGAGGTTCAAGAGATTCTTGTGCCTCAGCCTCCCGGATAGCTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000446.7
Synonyms	ESA; MVCD5; PON
Summary	This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017]
Locus ID	5444
MW	49.1

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