PON1 (NM_000446) Human 3' UTR Clone
CAT#: SC207986
3' UTR clone of paraoxonase 1 (PON1) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | PON1 (NM_000446) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | ESA; MVCD5; PON |
ACCN | NM_000446 |
Insert Size | 1298 bp |
Sequence Data |
>SC207986 3’UTR clone of NM_000446
The sequence shown below is from the reference sequence of NM_000446. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTTCACAAAGCTCTTTACTGTGAGCTCTAACAGACCGATTTGCACCCATGCCATAGAAACTGAGGCCAT TATTTCAACCGCTTGCCATATTCCGAGGACCCAGTGTTCTTAGCTGAACAATGAATGCTGACCCTAAAT GTGGACATCATGAAGCATCAAAGCACTGTTTAACTGGGAGTGATATGATGTGTAGGGCTTTTTTTTGAG AATACACTATCAAATCAGTCTTGGAATACTTGAAAACCTCATTTACCATAAAAATCCTTCTCACTAAAA TGGATAAATCAGTTATGTCAATTGTCAGATATTAAATAACAGTGTGTGACCCCAAAAGTACTTACCCTA AAACATGTGTTGCCTGGAAGCACATGTGTGTATCGCTGCCTTGCCATGTCTTGTTCAGAAGACACAGGG GAGCAGGGTTAGCTCACGTGTCTTTAGAACTCCAGTACTCACCCAGGGACTCCAGTTCACAGGCCAGAA AACATATGCATTATGAAGTTCCCCTCTACTCCATGCACATAGTAAGTCTGACTATGGCAGTCAGACTTA CTTACTCCCATTTTCCCTTCGATATATGACTTTTTCTCAGTAAATATTAACCTGAATTATTCCAACTCC CCTTGTACTCTTGCTTTTTCAATTCTCCTGTTGCAATGACACATAGGAAAATCTTAAAATTCTTGGGAG TGTTGTCACACCTGAAAATTATGAGTCTCTATGATCTTGGCACAAATTGTACATTTGAGTGTCTTTGAC TTGGTTAAAGGAAGTTTGTTCACTTCGATGACTGGATACAGAATGAATCCCATAATTGACATGGGCGAA GCTAAAAGTGTCCCCAAAGACTACACTGTTGTTGAGGTGGTGGTAGTGCTGGTGGGTTTTTGTTTAATA TTTAAACTTCTTGTTGTGGAGGCTGAAAAGAAAAAAAATAATAGAAAGGTAAACAAACAAATAAATAGA AAAGATCAACAACCCCTTTGGCTATCTACTGAGACATGACTAGGAAGAAAACATGACTTTATCATTTTG TTATAGAAACTGATATATAAAGGTTACACATTTTCATTTATTTGTTTTTCTGATTTGAAGGTATAACCT TCATGATGAATTACTTCTTCAGGGTGTTAAGGCAGTGACTTTAGAAACAAATTTTTTTCTTGTTTTTGT TTTGTTTTTGAGACCGAATCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTG CAACTTCTACCTCCGAGGTTCAAGAGATTCTTGTGCCTCAGCCTCCCGGATAGCTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_000446.7 |
Synonyms | ESA; MVCD5; PON |
Summary | This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017] |
Locus ID | 5444 |
MW | 49.1 |
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