QPRT (NM_014298) Human 3' UTR Clone

Specifications

Product Data
Product Name	QPRT (NM_014298) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HEL-S-90n; QPRTase
ACCN	NM_014298
Insert Size	1318 bp
Sequence Data	Insert Sequence (showhide) >SC207976 3’UTR clone of NM_014298 The sequence shown below is from the reference sequence of NM_014298. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGGTGGCTCCAGTGCCCAAAATCCACTAGTCCTAAACCGGAAGAGGATGACACCGGCCATGGGTTAAC GTGGCTCCTCAGGACCCTCTGGGTCACACATCTTTAGGGTCAGTGGCCAATGGGGCACATTTGGCACTA GCTTGAGCCCAACTCTGGCTCTGCCACCTGCTGCTCCTGTGACCTGTCAGGGCTGACTTCACCTCTGCT CATCTCAGTTTCCTAATCTGTAAAATGGGTCTAATAAAGGATCAACCACATGGGGTTCTGCGGTGATAA TGAGCACATAGTGAGGGGTCAGCAAATGTCAGAAGTTACCTGGGACAGCCGGGCACGATGGCTCACACC TGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGAAGATCACTTGAGTTCAGGAGTTTGAGACCAGCCTG GCCAACATGGTGAAACCCCATCTCTACCAAAAATAGAAGAATTAGCTGGGTGTGGTGGCACGCGCCTGT AATCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAAGTGGAGGTTGCAGTGAGC TGATGGTGCCACTGCACTCCAGCCTGGGTGATAGAGCGAGACTCTGTCTCCAAAGAAGAAACAAAGGAA AGAAAGAGAGAAAGAGAGAGGGAGGGAGGGAGGGAGGGAAAGGAAGGATGGAAAGAAAGGAAGAAAGGC AGGCAAAAGCCCCAGACAGGCCAAAACCTTCATCCTTCATGCACCCAACCTGTACCAAACACCAGCATG GCCTGGCTGTGAGTGCACAGCAGATGGAGGTTTGCTGGGCAGAGACACTGGGCTGGCCTAGACACTGCC TTTGGTGATACCCTAAACCAAAGGGGCCAGTCCCACAGTAAGAAGGAGACCACTACTACTCCTGCTGCC CTCCTCCCCCCACCTTGCCTAGTTTACAAGACAGGAGGAAAGAGAGAAAGCAAAAAGTTAGAAAACAAA ACAAAACAGAAGTAAGATAAATAGCCAGAAGACCTTGGCGACACCACCCGGCCCTGGTAGTTAAAAAAA AGTAACAATAATAATAATATCAACCCCTGACCTAAACTACTTGTGTTATCTGTAAATTCCAGACATTGT ATGAAAAAGCATTGCAAAACTTTCTGCTCTGTTAGCTGATGCGTGTAGCCCCCAGTCACGTTCCCCGCT TGCTTGAGATATCATGACCCTTTCACGTGGACCCCTTAGAGTTGTAAGCCTTTAAAAAGGCCAAGAATT TCTTTTTCAGGGATCTCAGCTATTAAGATGCAAGTCTGCCAATGCTCCTGGCCAAATAAACCTCTTCCT TCTTTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014298.6
Synonyms	HEL-S-90n; QPRTase
Summary	This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Locus ID	23475
MW	48.9

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