LIAS (NM_194451) Human 3' UTR Clone

Specifications

Product Data
Product Name	LIAS (NM_194451) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HGCLAS; HUSSY-01; LAS; LIP1; LS; PDHLD
ACCN	NM_194451
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC207818 3’UTR clone of NM_194451 The sequence shown below is from the reference sequence of NM_194451. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGGCGTCACCTTAAGGTGAATTTTTCCTGAAAAATCTAGTGGCTAAAAGAAAAACAAAAGACCTCTAAA ACTTCAACAAGACCTTCAAGATCACAGAAATTTTTAAAATTTGATTCCAGTTAATAACAGAGGTGGTGC CAGAATGCCTGGACTGCAGTGGATGTGCCCCACCTCTTTGCTTAAAAAAAAAAATGTCAATAGCCAGGC ATAGTGGCTCACGCCTGTAATCCCAGCACTTTAGGAGGCCAAGGCGGGTGGATCACCTGAGGTCAGGAG TTCGAGACCAGCCTGGCCAACATGGTGAAATCCTGTCTCCACTAAAAACACAAAAATTAGTCAGGCGTG GTAGTGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGCAGGAGAATCACTTGAACCTGGGAGGGG GAGGTTGCAGTGAGCCAAGATCGCTCCATTGCCCTCCAGCCTGGGTGACAAGAGCAAAACTCCATCTCA AATAAATAAAAAGGAAAAAAAAGTCAATAAACTGTACAAATTTAATTACAGTAATTCATTTGGCTTTTA GTGTATCTTCTTTGTCCCAATTAAACAGTTGCTTGCTGTGATGTAATCTTAAAATATCTTTGTAAGAAT TTTCTTTTAACATAATTTTAAAATGCATTAAAAACATGGCATGGTGGCTCACACCTATAATCCCAACAT TTTGGGAGGCCAGGGCGGGTGGATCACTTGAACCCAGGAGTTCGAGACCAGCCTGGGCAACATGATGAG ACCTTATCTCTACAAAAAATTAGCCAGACGTGGTGGCACGCACCCGTAGTCCCAGCTACTCAGGCTGAG GTGAGAGGATCACTTGAACCTGGAAAGCAGAGGTTGCAATGAGCTGAGGTGGTGCCACTGCTCTCCAGC CTGGGCGCTACAACTGCTCTCCAGACTCTGTCTTGAAAAAAAAACCCAAAAACTTCCAGAAGATTTTCC AATCCACTGTTAACATCATTACATTTCATTTATGAAAAATAAAAACTTCATTTATGTTACTGTGATGAA ACAGTCAACATAGATTGAAACTCATCAGTTTAGCATTTCATTCAACTTTAGCATTCATTCAACGTAGAT TGAAACTCATCAGATTAGCATTTGTCCTTGTAATATTGGAATAATTTAGAAAGGCTTAAGAGTGAATGT TGGCCAGATGTGGTGGCTCATGCCTGTAATTCCAGCACTCTGAGAGGCCGAGGTGGGCAGATCACCTGA GGTCGGGAGTTTGAGAACAGCCTGGCCAACCTGGTGAAACTCCATTGCTACTAAAAATAAAAAAATTAG CTAGGTGTGTTGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCACGAGAATTACTTGAGCC TGTGAAGCAGAGATTGCAGTGAGGCGATATCGTGCCACTGCACTCCAGCCCGGGCAACAGAGTGAGACT GTCTCAAAAAAAAAGTAAATGTTGATTTTTTACATTGGTGTGACTACTTCAGAACCTGCAAAATAGTTT TATGCTGATTACATTTAGTCCCTCTGAAAACACCAAGGCCATAATGCTGCCTAAGACATGGAAATAGAA CCTAGAAATATTAACCCTTATTTGTATAGTAGCTTGCTAAATCCACATGCCCTATTCCTTTCATTTCTC ACATTGGTTGTATTATATGATGGTAAAGGCCTGAGAAAGGAATTTCCTTCCAAAATACTAATAACTCAG ATTCATCTTTTGACTGAATCCTGCCTTTCTACTTTTTCTGCATATCTAAAAGGACACTTTTAGGTGGCC ATGTTGTAAAATATGTAAAGTGGATAGCCAATTCTGTTTTGAATTCTTATAACGAGCCAGTATTATAAA AGTAATGCACATCCTTGCCAGGTGTGGTGGCTCACGCCTGTAATCCCACCACCTTGGGAGGCTGAGGCG GGTGAATCAGTTGAGCTCAGGAGTTTGAGACTAGCCTGGGCAACACAGTCAGACCCCCATCTCTACCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_194451.3
Synonyms	HGCLAS; HUSSY-01; LAS; LIP1; LS; PDHLD
Summary	The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. Localized in the mitochondrion, this iron-sulfur enzyme catalyzes the final step in the de novo pathway for the biosynthesis of lipoic acid, a potent antioxidant. The deficient expression of this enzyme has been linked to conditions such as diabetes, atherosclerosis and neonatal-onset epilepsy. Alternative splicing occurs at this locus, and several transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Aug 2020]
Locus ID	11019
MW	74.9

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