B Raf (BRAF) (NM_004333) Human 3' UTR Clone

Specifications

Product Data
Product Name	B Raf (BRAF) (NM_004333) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	B-raf; B-RAF1; BRAF1; NS7; RAFB1
ACCN	NM_004333
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC207797 3’UTR clone of NM_004333 The sequence shown below is from the reference sequence of NM_004333. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGGGGATATGGTGCGTTTCCTGTCCACTGAAACAAATGAGTGAGAGAGTTCAGGAGAGTAGCAACAAAA GGAAAATAAATGAACATATGTTTGCTTATATGTTAAATTGAATAAAATACTCTCTTTTTTTTTAAGGTG AACCAAAGAACACTTGTGTGGTTAAAGACTAGATATAATTTTTCCCCAAACTAAAATTTATACTTAACA TTGGATTTTTAACATCCAAGGGTTAAAATACATAGACATTGCTAAAAATTGGCAGAGCCTCTTCTAGAG GCTTTACTTTCTGTTCCGGGTTTGTATCATTCACTTGGTTATTTTAAGTAGTAAACTTCAGTTTCTCAT GCAACTTTTGTTGCCAGCTATCACATGTCCACTAGGGACTCCAGAAGAAGACCCTACCTATGCCTGTGT TTGCAGGTGAGAAGTTGGCAGTCGGTTAGCCTGGGTTAGATAAGGCAAACTGAACAGATCTAATTTAGG AAGTCAGTAGAATTTAATAATTCTATTATTATTCTTAATAATTTTTCTATAACTATTTCTTTTTATAAC AATTTGGAAAATGTGGATGTCTTTTATTTCCTTGAAGCAATAAACTAAGTTTCTTTTTATAAATTTTGA GTGCAGGTGACCAAAAATATTGCTGAGGAGTGGCACGTTTGACATGAGTAAAATGTCTTAACTTCGGAT TTTTAGCGGGAAAATGTTATAAATTGGAGTTTCTTTTAAATAGCTTTTTTTAAAATACATTAAGGATGT CTCGCTCATGTAGAAGTCAAATTTTGTTGCAAACGCATTGCTCCCTTCACACCCAATCTCTCCCCTGCA AAAAATCTTCACAGAATTCTGTGAGAACTTTTAGGTGTGTTTTTCTTTGAGATACCTCTGGTTGCCAAA CACCAGGTAATAGATTTTTTAAAGTTGTTATTAGATTATTCTTACCTCTCATGATGCATATTTTAGCAA TCACCTTATCATTGTGTCTCATGTTCTGTCCTCCTTATATTCTTTGCCCAGCAAGATTCTACTTATGAT GAATGAATGCTCTTCTCCTTTTTTCATTCAATGGTATGAAGTATTTGTTAGGGTTCTTTAGTACTTACA CTTTGTTGTGTAGAAAATGACTGTAATGTGGTGGTCAGTGTATTCTTACTGTGATTCAGAGGGAATCAA AAGTAGAAAGCAACAGCACGTGGTCCTATCAAAGATTTGGCCATCTCTGCTTCACTGTCAGCCTCTTAA CTATATCTTCACTTACTCAATTTGGTTTTGTCATGATTTTTAAATGTAGCCAATAGATCAAGGTTCTTC CAGTAAACACATATCTGCATAAATGCCTCCTTGAAGTCAATAAAGAAGGAAATTGAGAAGACTTTAAAT TAATGATAATTTAGTTTTTAAGTACCCACAAATAAATTTTTGAAACATTTTCTTTATTTGAATACTTAG ATGTCATCCAGGAAAATCACTCAATAATAATTACGGCAAATCTTTAACCCCTCATTTGGGTAGCTTAAG ATAAGTAATGCCATTATGAATCAGAATTGATTCATGACTTTAGTTAAGAAAATGAAAAGGAACATTTCA CGTATTTTTAAAAATGATACTAAGGAATAAAGAAGTACAACTATTGGAAAATATCTAAGTATATGATTT TTAAATCCTCCAGTGGCATTAAATATATGATTATTAGTAATTGTTAGATAGGGTTTTATTCATTCACAA ATAGAAGACTAGCAAGCATGTAACTAACAAAGTTTTTACAAAATTGACTTTGTGGAATGCTCCAAATGT TTGGCCATTTTGAGGCACAAGGTCAGGGGTCTCTTTATTGATAGAGCTCCTTCTATAATTTCCCAGCAT ACCTGCCTCACAGTTATCTTCCTTTCATTGTTCACTCTCTTTTTCTTCTCAATGCCATCCTGCCTAGGC TCCCATCATCTGCATCTGACACCTTTCCTTTCTTTCTTTACTAGTCTCCTTTGCGATGGGTGTGGCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004333.6
Synonyms	B-raf; B-RAF1; BRAF1; NS7; RAFB1
Summary	This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
Locus ID	673
MW	77

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