SCN7A (NM_002976) Human 3' UTR Clone

Specifications

Product Data
Product Name	SCN7A (NM_002976) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	NaG; Nav2.1; Nav2.2; SCN6A
ACCN	NM_002976
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC207380 3’UTR clone of NM_002976 The sequence shown below is from the reference sequence of NM_002976. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAAAGTCACCTATTCAAAGCCAGATCTAATACCACTTACCACCTCTTTTCATATTTCTTCACATATCT GAAAAATGTTGAAAGCCTAAGCCAGGAATAAAAGAAAAGTAGAGATAATAATCAGTTCTTTACAACCGA TGGTAATTAAGCTTGTATTCACAAGACTTCATGCCAAATTCACTTTTTAGCATTATATCTAACAAATCA AGAGAATCCTTAATATTGCTGCAGTGAGTTTAAAGTGGGTTAAAGTGGCCATTTGACAATCTCATATTT GTTTTCTCTACATGGCTTATATGATGTGTGCCTTCTAGGGAATGAAGGGAAGTGGTGATAGAGATCAGC AGCAGCAGGGGCTTTCTTTTATATTTTATGTATAATTTAATGGGCTTTAAGTCACCACTATTAAGACTT ACAAATAAGCAAATACTTTCCTGATGTGGGATGGTGAAATGCTAATGGCCATTAAATCATAAACTTGCC TAGACAAAAGCCAATTGGAAGAAGGGAGAGAGCAGTTCTTTAGAAAGTGCCTTTGAGATCAACCTCAGA GATTCTTGGGCTGATTAAAACTGCATTTGAAAAAGATTGGTTGAAGCTCTGTGTTTATTTTTGTATGTT CTTGTTTTCATTTGGAACTGGGAATGAATAGGATTTCATTGTGCTCAAGCTCCTGGTTTCTCATCTCTG GATAGTTTCACCTAAGCTCTGGCTCTTAAGCAGGACAGATTCGTAAAACAAGAAGCATAAAGGAGAGGT ATAGCCTTTTTTTTTTTTTTTTTTTTCATTTTCTTCTCATTTACACCTATTTTTTTAAAAAGTATACAT TTACTAAAATGATGTAATAAATAACATGTTAATAGACTCAAGCTTTACCTTATGAAATTGATGTATTTT TACCAGTTATTTCTAATGTAACATTGAATATATAAGATCTGACAAATGTATGTTTAAACATGAATTAGA AGAGTTGAGAACTACCATTATGTATAGGGATTCTCATAGTGTCTTGGCCCTTAATTGGAAAGTTGTGGC AACTTTAAAGTACTTTTTACTGTATGTTATAATTCTTTATAACTTAGAGAGAGACAATGGTCACTCAAA CTATGAGAACTATGAATTAGGAGATAAAAGTTTAAATTTGTTGTTGTTTTATAACAGTATGTACAAGTT AGTTTTCCCTTATATATTTACGTTTTCAAGTTTTTTAATCTCATCATATACATCCATACTCTATAAAAT GTTTTATATTCAAAGAACTGTAAAATCCTAAACATTAGTTTTCACTATTGAAATTGTTTTTTAAAGATA GGCATAAATAGTTGTCCTTAGACTTATTCATACAAATATAGTCATTTACTTCTATGTAGTTTGAGATTC TGAGAGTTATTCCAACTTTATGAAGATTGATTTCAATGTGCCTGCTAAGTCCTAAAAGATTCAGAAAGA AAATTTATATATTATTGATTTAAATATCATCCTTTAAATATGTTGTATAACATTCAATATAGTTTATGT ATCAGTGATTGTATTTTATTCTGAATGCATGATCTCAAGCCTTAACTACTATAATCTTTTTCTGCCCCT CAGAAATTGAATAACCTAACCAAGATGCCTTTAGGGGATGCCCTAAGTAAATGTAATTTCAGATTTCAG GGTTTTTTTTTTTTCCTCTCTAAGTGTTCCTTCCCTTTCTTCTCCTGCTCTCCATCATGTTATGGAGAC CAGTGAGGAACCAGTGTTAACTTGGTGACAATGTGACAGCTGGTGCTTTATCTAAGCTCCGTTTTCTAT TTCTTGGGAATGCTTTATTGTGGAAACTGCTTCAGATACTTAAATTGAATCATAACTTGCTTCTGTAAA TTGCGTAAAGACAACAAACTGATTTTAGTTTGAAAAGTTTATCTTTTACTTGTAAACCTTGTTTGCCAG TTACCTTCCGAAAGCTGTGTAAAGAGTTATTTTTAACAAAGTCTTAACAATATATGTTACTTTTTAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002976.4
Synonyms	NaG; Nav2.1; Nav2.2; SCN6A
Summary	This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
Locus ID	6332
MW	78.8

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