Phospholipase A2 (PLA2G4A) (NM_024420) Human 3' UTR Clone

Specifications

Product Data
Product Name	Phospholipase A2 (PLA2G4A) (NM_024420) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	cPLA2; cPLA2-alpha; GURDP; PLA2G4
ACCN	NM_024420
Insert Size	503 bp
Sequence Data	Insert Sequence (showhide) >SC206556 3’UTR clone of NM_024420 The sequence shown below is from the reference sequence of NM_024420. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGGAGTTTCTAAGTAAACCCAAAGCATAGTTCATGTACTGGAAATGGCAGCAGTTTCTGATGCTGAGG CAGTTTGCAATCCCATGACAACTGGATTTAAAAGTACAGTACAGATAGTCGTACTGATCATGAGAGACT GGCTGATACTCAAAGTTGCAGTTACTTAGCTGCATGAGAATAATACTATTATAAGTTAGGTTGACAAAT GATGTTGATTATGTAAGGATATACTTAGCTACATTTTCAGTCAGTATGAACTTCCTGATACAAATGTAG GGATATATACTGTATTTTTAAACATTTCTCACCAACTTTCTTATGTGTGTTCTTTTTAAAAATTTTTTT TCTTTTAAAATATTTAACAGTTCAATCTCAATAAGACCTCGCATTATGTATGAATGTTATTCACTGACT AGATTTATTCATACCATGAGACAACACTATTTTTATTTATATATGCATATATATACATACATGAAATAA ATACATCAATATAAAAATAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_024420.3
Synonyms	cPLA2; cPLA2-alpha; GURDP; PLA2G4
Summary	This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Locus ID	5321
MW	20.7

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