PON2 (NM_000305) Human 3' UTR Clone

Specifications

Product Data
Product Name	PON2 (NM_000305) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_000305
Insert Size	498 bp
Sequence Data	Insert Sequence (showhide) >SC206539 3’UTR clone of NM_000305 The sequence shown below is from the reference sequence of NM_000305. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACCACAGAGCCTTGTATTGTGAACTCTAAATTGTACTTTTGGCATGAAAGTGCGATAACTTAACAATT AATTTTCTATGAATTGCTAATTCTGAGGGAATTTAACCAGCAACATTGACCCAGAAATGTATGGCATGT GTAGTTAATTTTATTCCAGTAAGGAACGGCCCTTTTAGTTCTTAGAGCACTTTTAACAAAAAAGGAAAA TGAACAGGTTCTTTAAAATGCCAAGCAAGGGACAGAAAAGAAAGCTGCTTTCGAATAAAGTGAATACAT TTTGCACAAAGTAAGCCTCACCTTTGCCTTCCAACTGCCAGAACATGGATTCCACTGAAATAGAGTGAA TTATATTTCCTTAAAATGTGAGTGACCTCACTTCTGGCACTGTGACTACTATGGCTGTTTAGAACTACT GATAACGTATTTTGATGTTTTGTACTTACATCTTTGTTTACCATTAAAAAGTTGGAGTTATATTAAAGA CTAACTAAAATCCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000305.3
Summary	This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Locus ID	5445
MW	19.1

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