LXR beta (NR1H2) (NM_007121) Human 3' UTR Clone

Specifications

Product Data
Product Name	LXR beta (NR1H2) (NM_007121) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	LXR-b; LXRB; NER; NER-I; RIP15; UNR
ACCN	NM_007121
Insert Size	816 bp
Sequence Data	Insert Sequence (showhide) >SC205737 3’UTR clone of NM_007121 The sequence shown below is from the reference sequence of NM_007121. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGTCGGAGATCTGGGACGTCCACGAGTGAGGGGCTGGCCACCCAGCCCCACAGCCTTGCCTGACCACC CTCCAGCAGATAGACGCCGGCACCCCTTCCTCTTCCTAGGGTGGAAGGGGCCCTGGGCCGAGCCTGTAG ACCTATCGGCTCTCATCCCTTGGGATAAGCCCCAGTCCAGGTCCAGGAGGCTCCCTCCCTGCCCAGCGA GTCTTCCAGAAGGGGTGAAAGGGTTGCAGGTCCCGACCACTGACCCTTCCCGGCTGCCCTCCCTCCCCA GCTTACACCTCAAGCCCAGCACGCAGTGCACCTTGAACAGAGGGAGGGGAGGACCCATGGCTCTCCCCC CTAGCCCGGGAGACCAGGGCCTTCCTCTTCCTCTGCTTTTATTTAATAAAAACTAAAAACAGAAACAGG AAAATAAAATATGAATACAATCCAGCCCGGAGCTGGAGTGCAAGATGGAGAGGGCGCGGGCTTCTAGGG ACCTCAGTGACACTGGGTGCCCGAACCTGATTGAGCAGGTGGGACTGGGTGTCCCCAGGCTGTTGGGAA AAGGGTGGCACATAGGGTCCCAGTGTTGGGTGGTGTGTCGCCTGCTGTGAAAGTTCAGGACAGAGGCCT CAGCCTCAGGGTCACCTCCCTGGACAAGGTGAATCAGAACTCACCCTTGAAGGATAAACAGGATTTAAG TGAATGAGGGGACCTGGACTTCTGTCCGAACAACAAGTGTTTGCTGAGGCCTCCTGTGGGCCAGGCACT GGGTTGGCCATTCTAGAGATGGAGACATTCACCCAATAAATGTTTCCAGAGCATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_007121.7
Synonyms	LXR-b; LXRB; NER; NER-I; RIP15; UNR
Summary	The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
Locus ID	7376
MW	29.1

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