CCM2 (NM_031443) Human 3' UTR Clone

Specifications

Product Data
Product Name	CCM2 (NM_031443) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C7orf22; OSM; PP10187
ACCN	NM_031443
Insert Size	426 bp
Sequence Data	Insert Sequence (showhide) >SC205724 3’UTR clone of NM_031443 The sequence shown below is from the reference sequence of NM_031443. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCTGCAGCATGGACCAGGACTCAGCATGATGGACAGTGGATGGGGGGGCACCCACACCTTCCGCGCAG TCGTCATAGGCCTTCCCAGAAGGAGCTGCCCAGACCTGCGTGTCAGCCCTTGGTGGTGGCCAGGGAGAG GCGCCCGGTGCAGATGGCCCCGGGCGGCCCAGGTCCTCTACTGTGAAGGAGCAGGGAGCTGCCGAGGGA CACGAGCCTCAGTGCGGGGTGGAAGGCTCTTTGCCTTGTCCACCAGGGCTCAGCCAAGCCCTGCAGTGT GTCCCCGCTCGGGGAGGGCCCGGCCGAGCGGGCAGGGAGAGCCAGTCCTGTCGGCTGGGCCCTTGGACG GCTGTCAGTTTTGCACATGATGTTCCTATTGTAACTCTCAGAGACCTTAAAAAGAAGTTTACTGCAATG TGAATAATTTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_031443.4
Synonyms	C7orf22; OSM; PP10187
Summary	This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Locus ID	83605
MW	14.2

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