BAD (NM_004322) Human 3' UTR Clone

Specifications

Product Data
Product Name	BAD (NM_004322) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BBC2; BCL2L8
ACCN	NM_004322
Insert Size	400 bp
Sequence Data	Insert Sequence (showhide) >SC205331 3' UTR clone of NM_004322 The sequence shown below is from the reference sequence of NM_004322. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GGTGGGATCGGAACTTGGGCAGGGGAAGCTCCGCCCCCTCCCAGTGACCTTCGCTCCACATCCCGAAACT CCACCCGTTCCCACTGCCCTGGGCAGCCATCTTGAATATGGGCGGAAGTACTTCCCTCAGGCCTATGCAA AAAGAGGATCCGTGCTGTCTCCTTTGGAGGGAGGGCTGACCCAGATTCCCTTCCGGTGCGTGTGAAGCCA CGGAAGGCTTGGTCCCATCGGAAGTTTTGGGTTTTCCGCCCACAGCCGCCGGAAGTGGCTCCGTGGCCCC GCCCTCAGGCTCCGGGCTTTCCCCCAGGCGCCTGCGCTAAGTCGCGAGCCAGGTTTAACCGTTGCGTCAC CGGGACCCGAGCCCCCGCGATGCCCTGGGGGCCGTGCTCACTACCAAATG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004322.3
Synonyms	BBC2; BCL2L8
Summary	The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019]
Locus ID	572

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