MRPS12 (NM_033362) Human 3' UTR Clone

Specifications

Product Data
Product Name	MRPS12 (NM_033362) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MPR-S12; MT-RPS12; RPMS12; RPS12; RPSM12
ACCN	NM_033362
Insert Size	498 bp
Sequence Data	Insert Sequence (showhide) >SC205239 3’UTR clone of NM_033362 The sequence shown below is from the reference sequence of NM_033362. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACGACTGTGGCCACGTGCAGAAGAAGTGACGGCTGGGGGCACAGTGGGCTGGGCGCCCCTGCAGAACA TGAACCTTCCGCTCCTGGCTGCCACAGGGTCCTCCGATGCTGGCCTTTGCGCCTCTAGAGGCAGCCACT CATGGATTCAAGTCCTGGCTCCGCCTCTTCCATCAGGACCACTATTAAGCCATAGGAGTCCTGGGGGTG CAAAGGGTGCCCCTCTGTCAACACCCTTGGCTCCTGTGTTTAGAGGGGTGGCCTGAAGGACCTTTTCTG CTGGGACAAGACACTGTACTGCCCTCTGCTGGGAAGGGGTTTTAATAAACAGACCCTGGCGCTTGTGAT GTAAATCCCCTTGTGGAGTATTTGCCCTCTGTGTGGCTGTGGCAGTGGACATCTCTGAGCTTCAGTTTC CTCCAGAAAATAGCTCCATTGGTGGTATCTCCTTTGTTTGGTTTGGTGAAGATTAAATTCGATGCTCTA TGTGCATAACACGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_033362.4
Synonyms	MPR-S12; MT-RPS12; RPMS12; RPS12; RPSM12
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein. [provided by RefSeq, Jul 2008]
Locus ID	6183
MW	18.6

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