ILF2 (NM_004515) Human 3' UTR Clone

Specifications

Product Data
Product Name	ILF2 (NM_004515) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	NF45; PRO3063
ACCN	NM_004515
Insert Size	369 bp
Sequence Data	Insert Sequence (showhide) >SC205153 3' UTR clone of NM_004515 The sequence shown below is from the reference sequence of NM_004515. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GCATGGAAACTCAGGAGTGACATTCCCTTCACTCCTTTTCCTACCCAAGGGGGAAGACTGGAGCCTAAGC TGCCTGCTACTGGGCTTTACATGGTGACAGACATTTCCGTGGGATAGGGAAGATAGCAGGAAGAAAAGTA AACTCCATAGAAGTGTCATTCCACTGGGTTTTGATATTGGCTTAGCTGCCAGTCTCCCATTTGTGACCTA TGCCATCCATCTATAATGGAGGATACCAACATTTCTTCCTAATATTCTATAATCTCCAACTCCTGAAAAC CCCTCTCTCAACTAATACTTTGCTGTTGAAATGTTGTGAAATGTTAAGTGTCTGGAAATTTTTTTTTCTA AGAAAAACTATTAAAGTAC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004515.2
Synonyms	NF45; PRO3063
Summary	The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014]
Locus ID	3608

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