HLA DP (HLA-DPA1) (NM_033554) Human 3' UTR Clone

Specifications

Product Data
Product Name	HLA DP (HLA-DPA1) (NM_033554) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DP(W3); DP(W4); DPA1; HLA-DP1A; HLA-DPA; HLA-DPB1; HLADP; HLASB; PLT1
ACCN	NM_033554
Insert Size	837 bp
Sequence Data	Insert Sequence (showhide) >SC204584 3’UTR clone of NM_033554 The sequence shown below is from the reference sequence of NM_033554. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CATGACCCCCGGGCCCAGGGGACCCTGTGAAATACTGTAAAGGTGACAAAATATCTGAACAGAAGAGGA CTTAGGAGAGATCTGAACTCCAGCTGCCCTACAAACTCCATCTCAGCTTTTCTTCTCACTTCATGTGAA AACTACTCCAGTGGCTGACTGAATTGCTGACCCTTCAAGCTCTGTCCTTATCCATTACCTCAAAGCAGT CATTCCTTAGTAAAGTTTCCAACAAATAGAAATTAATGACACTTTGGTAGCACTAATATGGAGATTATC CTTTCATTGAGCCTTTTATCCTCTGTTCTCCTTTGAAGAACCCCTCACTGTCACCTTCCCGAGAATACC CTAAGACCAATAAATACTTCAGTATTTCAGAGCGGGGAGACTCTGAGTCATTCTTACTGGAAGTCTAGG ACCAGGTCACATGTGAATACTATTTCTTGAAGGTGTGGTTTCAACCTCTGTTGCCGATGTGGTTACTAA AGGTTCTGATCCCACTTGAACGGAAAGGTCTGAGGATATTGATTCAGTCCTGGGTTTTTCCCTAACTAC AGGATAGGGTGGGGTAGAGAAAGGATATTTGGGGGAAATTTTACTTGGATGAAGATTTTCTTGGATGTA GTTTGAAGACTGCAGTGTTTGAAGTCTCTGAGGGAAGAGATTTGGTCTGTCTGGATCAAGATTTCAGGC AGATTAGGATTCCATTCACAGCCCCTGAGCTTCCTTCCCAAGGCTGTATTGTAATTATAGCAATATTTC ATGGAGGATTTTTCTACATGATAAACTAAGAGCCAAGAAATAAAATTTTTAAAATGCCCTAAAAAAAAA AAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_033554.3
Synonyms	DP(W3); DP(W4); DPA1; HLA-DP1A; HLA-DPA; HLA-DPB1; HLADP; HLASB; PLT1
Summary	HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
Locus ID	3113
MW	32.2

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