ATP6V1B1 (NM_001692) Human 3' UTR Clone

Specifications

Product Data
Product Name	ATP6V1B1 (NM_001692) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ATP6B1; DRTA2; RTA1B; VATB; VMA2; VPP3
ACCN	NM_001692
Insert Size	340 bp
Sequence Data	Insert Sequence (showhide) >SC204335 3’UTR clone of NM_001692 The sequence shown below is from the reference sequence of NM_001692. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGACCTCGCGCCTGACACTGCGCTCTAGCCCCGCGCGCCGTGGCACCCCAACACCGGCAGGGAACCT ACCCTCGGCTCCCGGGTCTCCCCTCCCTCGCCACCCCAACCAGCGGCTTCTGCGCCGCCCTCCGCCCTC CGCTGGCTCCGAGGTGGTGGGGGCGCCGCACGCTCCATCCCTTTCCCTCGCTCGATTCCTTTTCCCGCG CTCCATGCCTCCCCCTCGACTCCCGGTGCTGCGGAAGAACTGAAGGTTGCGATGCCTTACTCTGACGGG AGCATCTGTATTTTTATGTTAAAAGCCCACAAAATAAAAATAAAAAGTAACTGAGATGAATTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001692.4
Synonyms	ATP6B1; DRTA2; RTA1B; VATB; VMA2; VPP3
Summary	This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq, Jul 2008]
Locus ID	525
MW	12

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