PLCG 2 (PLCG2) (NM_002661) Human 3' UTR Clone

Specifications

Product Data
Product Name	PLCG 2 (PLCG2) (NM_002661) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	APLAID; FCAS3; PLC-gamma-2; PLC-IV
ACCN	NM_002661
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC204122 3’UTR clone of NM_002661 The sequence shown below is from the reference sequence of NM_002661. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGAGTCAGCAACAGCAAGTTTTACTCATAGAAGCTGGGGTATGTGTGTAAGGGTATTGTGTGTGTGCGC ATGTGTGTTTGCATGTAGGAGAACGTGCCCTATTCACACTCTGGGAAGACGCTAATCTGTGACATCTTT TCTTCAAGCCTGCCATCAAGGACATTTCTTAAGACCCAACTGGCATGAGTTGGGGTAATTTCCTATTAT TTTCATCTTGGACAACTTTCTTAACTTATATTCTTTATAGAGGATTCCCCAAAATGTGCTCCTCATTTT TGGCCTCTCATGTTCCAAACCTCATTGAATAAAAGCAATGAAAACCTTGATCAATTAAGCCTTCTGTTG CACGACCTGTGCAGTGAACAGGATTTCTTTTCTGGCCAAGAAGATTCTACCTCTAATGATCCAGGTAAC TGATGTCCATGGAGGATGAGCTGGAAATGTAAGAAACTATTCATGAGATTCTGAAAAGGATTTTAACTC AAAGGCAAATGATTCCATAAGGGCCCAAAGAGAAGCCCTACCCACAGGCAGCCTGCTCAGTTCAATGTA CTTTAACTACCACCGGCTGCCTGCTGCAGTCCACAAGAAAATGGCTGAGTGATGGGATCTGTTCATTAA GACAATTTCTAATTAATGGTGACAGCTTGTTTTGTGACTAGAGTTACTGGGATGGAGGGTAGGAATCTT GGGGCCTCTTTGTTTTAAAAAGCCCATCAGAGAGACCAGAGCCGTGCTGCAGGGGCAGGTTCTCACTTG CCCCTGGCTCTGCCAGCTGCTGGGAGGCTCTGGCCCCACTAGTCCCTCATGGCCCTACTGAACTGGCTG GGAGGCTGCTGGAATGGCCCTTGGTCCACAGCTCTCCACAGGCAAGAGGTCAACTGCTGCTTGAAAGAG GTAGACAAAAGTTAGGTTGATGGCGAAATGTCTCTGGGTTACCCAGTCTTCTGGAGCAGCAAGCTGAGC TTTAATGGGCTAAGCATTAGGGTGTTACAGAAAATTTCAAATGCAGCCATCTCCCTTGGGGCAGATCTA CCTAGTTCATGACAGTATGTGCGGCTGGCCAGGGCTTTACACCTCTGCATCTTAAGTTGTTAATACATA CCAATAATGTAATATGGCTTTTTAAAGGAGAGGAGAGTGCTGGGTTGGGAAGGGAGGTGGTTGGTAGAG TCACAACTTCTCAATGAGTGAATTTACAGCTGATGGGAAAAGGAGTGTAACTGTGAAAAACGATGGCTG TGGTGGGGAAGAACAAACCAGCAGTAAGCCTGATGTTTGATGTGGATGGAACTGGCCCCTAGAAACCCA TCTGACCCTCCTCTTGTTACCCGAAATGCTGGGCTTAGTATGCATGTACTGCTGAAAAGCAGGGCAGAA CAAATCAGGCTCTGACCAGAAGATCCTTCTGGTCCCTTCACTCTACAAAAACTTACTGATCACCTCCAC ATGCCAAATACAGTGCCAAGATTTGGGGGTGTGGATGTTTAAACAAAAAGCTGTGGGTCTCATCAATCA TCTCCATCCACAAGCTCCTAAAAGAAAGCCATTTACCTCGCTTGAAGCCAGGAACACAGGGAACAGCAG TCTGGCCAAGGAAGGGCTGTTATCTGGTGCTATCACTCCAGTTACTCCTCCAACTGGGAGCTGCTATTT TATTTGGCAGTCAGCAACTGAAGAAAGAACATTCCTCTTAGTGGCAGATGTTCAAAGCAACTTTCAAGA AAGGCTAGGTGAGAAAGGCACTGGGATGAGTGCTGCAGGCACTCTGTAGCCAGGGCCCCATTAGCCTTT GGCCAGGTAGCCACCAGAACCTATTTATTGCACCTGGCATCTCCCCCAACCCCTCTCAGCTCTGTTAGG ACTTCCACACAGCAGAGCTCAGGTGTTGCTGTCATTACCTCCTTTCAGCTCCTCACTTCATTCTACTTT AAAGCCACAGTGCTAAGGCCTGCATCCCCTTTCTGCCCAAATGGGTTTTTTGCTACCATATCAAAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002661.5
Synonyms	APLAID; FCAS3; PLC-gamma-2; PLC-IV
Summary	The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
Locus ID	5336
MW	75

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