FLAP (ALOX5AP) (NM_001629) Human 3' UTR Clone

Specifications

Product Data
Product Name	FLAP (ALOX5AP) (NM_001629) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FLAP
ACCN	NM_001629
Insert Size	350 bp
Sequence Data	Insert Sequence (showhide) >SC204119 3’UTR clone of NM_001629 The sequence shown below is from the reference sequence of NM_001629. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCATCTCCCCTCTACTTCTCATTCCCTAACTCTCTGCTGAATATGGGGTTGGTGTTCTCATCTAATCA ATACCTACAAGTCATCATAATTCAGCTCTTGAGAGCATTCTGCTCTTCTTTAGATGGCTGTAAATCTAT TGGCCATCTGGGCTTCACAGCTTGAGTTAACCTTGCTTTTCCGGGAACAAAATGATGTCATGTCAGCTC CGCCCCTTGAACATGACCGTGGCCCCAAATTTGCTATTCCCATGCATTTTGTTTGTTTCTTCACTTATC CTGTTCTCTGAAGATGTTTTGTGACCAGGTTTGTGTTTTCTTAAAATAAAATGCAGAGACATGTTTTAA GCTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001629.4
Synonyms	FLAP
Summary	This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Locus ID	241
MW	13

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