Caspase 10 (CASP10) (NM_032974) Human 3' UTR Clone

Specifications

Product Data
Product Name	Caspase 10 (CASP10) (NM_032974) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALPS2; FLICE-2; FLICE2; MCH4
ACCN	NM_032974
Insert Size	353 bp
Sequence Data	Insert Sequence (showhide) >SC203977 3’UTR clone of NM_032974 The sequence shown below is from the reference sequence of NM_032974. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCATGCGCAGGTGGAGCAGCGTTTCCTAGTTCTTTCCAGAGGCTTCCTTCTGCCTGCCTTCCAGCCAC ATCGCCTGAGATTGACAACGCCCTACAGCAAGACGGAAACCTCCCTTTACAGCACCACCTTGCGATTCT GCAGCCACAAAGTTGAGACTTCTGAACGTGGCACTCTTCTGTTCCCTTACTGTTTCACGTGTACCTGTG TCATCTTTCTTGTTTCATCGTAAACATACTTCTAAAATTCCCATTTTCTTTATTTAGAAATAGAACTAC AAGCGGATGGTTAAACAATTTAAACAAATGGTCCATGGGGAAAAGTGAATTTCACACTGTCCCCCAAAC TTTCAGTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_032974.5
Synonyms	ALPS2; FLICE-2; FLICE2; MCH4
Summary	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
Locus ID	843
MW	13.5

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