HTR2B (NM_000867) Human 3' UTR Clone

Specifications

Product Data
Product Name	HTR2B (NM_000867) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	5-HT(2B); 5-HT-2B; 5-HT2B
ACCN	NM_000867
Insert Size	317 bp
Sequence Data	Insert Sequence (showhide) >SC203738 3’UTR clone of NM_000867 The sequence shown below is from the reference sequence of NM_000867. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAACTGAAGAGCAAGTTAGTTATGTATAGCAGAACTGGCAGTTGTCATCAAACATAATGATGAGTAAG ATGATGAATGAGATGTAAATGTGCCAAGAATATATTATATAAAGAATTTTATGTCATATATCAAATCAT CTCTTTAACCTAAGATGTAAGTATTAAGAATATCTAATTTTCCTAATTTGGACAAGATTATTCCATGAG GAAAATAATTTTATATAGCTACAAATGAAAACAATCCAGCACTCTGGTTAAATTTTAAGGTATTCGAAT GAAATAAAGTCAAATCAATAAATTTCAGGCTTTAAAAAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000867.5
Synonyms	5-HT(2B); 5-HT-2B; 5-HT2B
Summary	This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Locus ID	3357
MW	12.8

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