ABHD12 (NM_015600) Human 3' UTR Clone

Specifications

Product Data
Product Name	ABHD12 (NM_015600) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ABHD12A; BEM46L2; C20orf22; dJ965G21.2; hABHD12; PHARC
ACCN	NM_015600
Insert Size	260 bp
Sequence Data	Insert Sequence (showhide) >SC203193 3’UTR clone of NM_015600 The sequence shown below is from the reference sequence of NM_015600. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GATCCCAGCATGTGGTCAGAGCTGGTGTGACTGAAGCCAACAGGTGACACGGTCATCGAAGAGCAGCAG ACAAAACTAAAACTAACCCAAAGGCAGCTGAAAGTGGAGGGCAGGTGAATTCCCAGCCCTCGCCGGATT CAACTTTTGCCAACGGTGAAGAACTGCCCTGAGCTGCAAACCTTACAAAGTCTGTAACTCTAGATAAAC CATACCATGTGCTAACTGCACTGAAATAAAACACTAACTACATTATAATGTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015600.5
Synonyms	ABHD12A; BEM46L2; C20orf22; dJ965G21.2; hABHD12; PHARC
Summary	This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]
Locus ID	26090
MW	9.9

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