ELOC (NM_005648) Human 3' UTR Clone

Specifications

Product Data
Product Name	ELOC (NM_005648) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SIII; TCEB1
ACCN	NM_005648
Insert Size	1541 bp
Sequence Data	Insert Sequence (showhide) >SC202987 3’UTR clone of NM_005648 The sequence shown below is from the reference sequence of NM_005648. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGATGGCTGCGAACTTCTTAGATTGTTAAATAAAATAAATTATAATAAACTGTTAACTCTTTTCAGTA TTTAATACCTGTAGTTCAGTTAGTAACTTTTTCATATATAGCATGTTGCCTGTATGCAGTTGAACTATA TAAAGTTCATTGCAAAGCAGATTATCTTGTTTTTTTGCATAGCAATCAAAGTTGAAATTTGTTTGCTAC ATCAACAAATTAAGGACATTTTCACAAACTGAGAAATAAACAAATATGCCAATTCGTAGGTGGTTTTGC CTTATCCTTTGAATGTGACTTAAAATCAGCAATGATGATATAGTAAATACTGAAATTTAGGTGTAAATC AATACGTTCTACAGGGAAATAATGAGGCTAAGTATTTTTATGTTTTTAGTGGTTTTTTAGAAACCTAAT CTTATAGCCGCCATTAGCATTACTAGAGTTATGCAAATAATTGCATTATAAACATGTTTATAACTTAGC CAAAACATTGATTTTTATAACTCTCCAAGTATGAGTTGAAATTTCTTATGTCTTTTGATAAACTGCAGT ATTCTTTAAGTGTACTTTGTCCTTTTGTTTATTGCTACAATTTAAGAACTTTATTTAAAAACAATTTTG GAAGGTTACTAGGTACAGCTTTTGCAGAAGAAACTGAACTGTAGCCAGATGGTCAGCAAGTAAACTACA TGACTTAGAGTTCTTGTGCATTATACATTTTGGGTAATTCAAAGTACTGTATTTGCATTGACTATAAAG CGTCGTTTGCAATATTTATTCTTCCTTCATAGTCCCTTGTTGTGATTATACTTCCAGTTGTTTAAATGT ATTTTAAAAGACTCACTATTAACTTTATTCAGATCTTAAAAGCTACACCTTTTTGAACTATTCCAGTCT TTCTCCATCCAATTAGAATGTTATGGAATAACATGTGAAGAGATACAGTGAAAATCATATTATAATGCA TTGAAGATATCCTACATGAATTATCTTCTATTAAAATATGTCCCAATAAATATACCCATAATCAGTGGG TCTTCTACTGAAATCAAGCTCATTCAGCTTTTCTATTAAGCAGCCAAAAAATTTTTTGAAAAAATATGA CAGCATCATTCCTTATGCATGGGGAAAGAAGCACTGGAGATGGGTTTAGTATTGTCTTTATCTCAGAGG TGGAACAAAGTTGTCATTATAGGGTCTATAAACTTAAGTCTCCAGCTTATTTGAGACTGGCTTAATATG GCTGAGCCCGGTGGCTCATGCCTGTAATCCCAGCACTTTCAGAGGACGAGGCGGGTAGATCACTTGAGG CCAGGAGTTTGAGACCAGCCTGGCCACCATGGCAAAACCCCATCTCTACCAAAAATGCAAAAATTAGCT AGGCCATGGTGGCACACGCCTGTAATCCCAGCTACTTGTGAGGCTGAGGCATGAGAATCGCTTGAACCT GGGAGGTGGAGGTGGCAGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTG TCTCAAAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005648.4
Synonyms	SIII; TCEB1
Summary	This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Locus ID	6921
MW	59.6

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