Apc5 (ANAPC5) (NM_001137559) Human 3' UTR Clone

Specifications

Product Data
Product Name	Apc5 (ANAPC5) (NM_001137559) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	APC5
ACCN	NM_001137559
Insert Size	265 bp
Sequence Data	Insert Sequence (showhide) >SC202825 3’UTR clone of NM_001137559 The sequence shown below is from the reference sequence of NM_001137559. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CATGGGGTACCCTTGATAAACCATCTCTAGAGAGGACATCCCTGCTGGGCTGCTGTGCAGAGTATAAGA TTTTGGACTTGTTCATGTCCCCTCTCTCCCTATAAATGATGTATTTGTGACACCCTATCTTGTCAATAA ACAGCATTCTGATTAGTTTGTCTTATTTTGTTGCTAGTAACTACGTATTTGTTTTATTCCCCTTTTCTT CCCTTTTGGTAGCAAAGGACACCAACTTTTTCTTAATAAATGGGTATTTTGCTAACAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001137559.1
Synonyms	APC5
Summary	This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
Locus ID	51433
MW	10.1

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